CEP170 (centrosomal protein 170)

2014-08-01  

Identity

HGNC
LOCATION
1q43
LOCUSID
ALIAS
FAM68A,KAB,KIAA0470
FUSION GENES

Other Information

Locus ID:

NCBI: 9859
MIM: 613023
HGNC: 28920
Ensembl: ENSG00000143702

Variants:

dbSNP: 9859
ClinVar: 9859
TCGA: ENSG00000143702
COSMIC: CEP170

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000143702ENST00000336415H0Y2V6
ENSG00000143702ENST00000366542Q5SW79
ENSG00000143702ENST00000366543Q5SW79
ENSG00000143702ENST00000366544Q5SW79
ENSG00000143702ENST00000413359H0Y4T4
ENSG00000143702ENST00000461671H0YB66
ENSG00000143702ENST00000464936E5RG47
ENSG00000143702ENST00000481987E7EMW0
ENSG00000143702ENST00000490813E7EWM2
ENSG00000143702ENST00000492145E5RGW7
ENSG00000143702ENST00000522191E5RFU8
ENSG00000143702ENST00000522895H0YB92
ENSG00000143702ENST00000522995E5RIH6
ENSG00000143702ENST00000523424E5RJT5

Expression (GTEx)

0
5
10
15
20
25
30
35

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
156161862005The forkhead-associated domain protein Cep170 interacts with Polo-like kinase 1 and serves as a marker for mature centrioles.99
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.62
230872112012The microtubule-binding protein Cep170 promotes the targeting of the kinesin-13 depolymerase Kif2b to the mitotic spindle.16
311971412019Modeling microcephaly with cerebral organoids reveals a WDR62-CEP170-KIF2A pathway promoting cilium disassembly in neural progenitors.8
290549272017The C-terminal region of A-kinase anchor protein 350 (AKAP350A) enables formation of microtubule-nucleation centers and interacts with pericentriolar proteins.4
196260402009Follow-up examination of linkage and association to chromosome 1q43 in multiple sclerosis.3
303547982018Ccdc61 controls centrosomal localization of Cep170 and is required for spindle assembly and symmetry.3
307099702019A SEPT1-based scaffold is required for Golgi integrity and function.2

Citation

Dessen P

CEP170 (centrosomal protein 170)

Atlas Genet Cytogenet Oncol Haematol. 2014-08-01

Online version: http://atlasgeneticsoncology.org/gene/54211/cep170-(centrosomal-protein-170)