CEP170 (centrosomal protein 170)

2014-08-01  

Identity

HGNC
LOCATION
1q43
LOCUSID
ALIAS
FAM68A,KAB,KIAA0470
FUSION GENES

Other Information

Locus ID:

NCBI: 9859
MIM: 613023
HGNC: 28920
Ensembl: ENSG00000143702

Variants:

dbSNP: 9859
ClinVar: 9859
TCGA: ENSG00000143702
COSMIC: CEP170

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000143702ENST00000336415H0Y2V6
ENSG00000143702ENST00000366542Q5SW79
ENSG00000143702ENST00000366543Q5SW79
ENSG00000143702ENST00000366544Q5SW79
ENSG00000143702ENST00000413359H0Y4T4
ENSG00000143702ENST00000461671H0YB66
ENSG00000143702ENST00000464936E5RG47
ENSG00000143702ENST00000481987E7EMW0
ENSG00000143702ENST00000490813E7EWM2
ENSG00000143702ENST00000492145E5RGW7
ENSG00000143702ENST00000522191E5RFU8
ENSG00000143702ENST00000522895H0YB92
ENSG00000143702ENST00000522995E5RIH6
ENSG00000143702ENST00000523424E5RJT5

Expression (GTEx)

0
5
10
15
20
25
30
35

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
351193602022α-/γ-Taxilin are required for centriolar subdistal appendage assembly and microtubule organization.2
351193602022α-/γ-Taxilin are required for centriolar subdistal appendage assembly and microtubule organization.2
307099702019A SEPT1-based scaffold is required for Golgi integrity and function.12
311971412019Modeling microcephaly with cerebral organoids reveals a WDR62-CEP170-KIF2A pathway promoting cilium disassembly in neural progenitors.86
307099702019A SEPT1-based scaffold is required for Golgi integrity and function.12
311971412019Modeling microcephaly with cerebral organoids reveals a WDR62-CEP170-KIF2A pathway promoting cilium disassembly in neural progenitors.86
303547982018Ccdc61 controls centrosomal localization of Cep170 and is required for spindle assembly and symmetry.8
303547982018Ccdc61 controls centrosomal localization of Cep170 and is required for spindle assembly and symmetry.8
290549272017The C-terminal region of A-kinase anchor protein 350 (AKAP350A) enables formation of microtubule-nucleation centers and interacts with pericentriolar proteins.8
290549272017The C-terminal region of A-kinase anchor protein 350 (AKAP350A) enables formation of microtubule-nucleation centers and interacts with pericentriolar proteins.8
230872112012The microtubule-binding protein Cep170 promotes the targeting of the kinesin-13 depolymerase Kif2b to the mitotic spindle.28
230872112012The microtubule-binding protein Cep170 promotes the targeting of the kinesin-13 depolymerase Kif2b to the mitotic spindle.28
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.78
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.78
196260402009Follow-up examination of linkage and association to chromosome 1q43 in multiple sclerosis.3

Citation

Dessen P

CEP170 (centrosomal protein 170)

Atlas Genet Cytogenet Oncol Haematol. 2014-08-01

Online version: http://atlasgeneticsoncology.org/gene/54211/cep170-(centrosomal-protein-170)