Identity
HGNC
LOCATION
7q32.3
LOCUSID
ALIAS
MICOS19,MINOS3,Mic19,PPP1R22
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 54927
MIM: 613748
HGNC: 21906
Ensembl: ENSG00000106554
Variants:
dbSNP: 54927
ClinVar: 54927
TCGA: ENSG00000106554
COSMIC: CHCHD3
RNA/Proteins
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Metabolism of proteins | REACTOME | R-HSA-392499 |
| Mitochondrial protein import | REACTOME | R-HSA-1268020 |
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 31097788 | 2020 | Sam50-Mic19-Mic60 axis determines mitochondrial cristae architecture by mediating mitochondrial outer and inner membrane contact. | 40 |
| 32788360 | 2020 | Multicolor 3D MINFLUX nanoscopy of mitochondrial MICOS proteins. | 35 |
| 31097788 | 2020 | Sam50-Mic19-Mic60 axis determines mitochondrial cristae architecture by mediating mitochondrial outer and inner membrane contact. | 40 |
| 32788360 | 2020 | Multicolor 3D MINFLUX nanoscopy of mitochondrial MICOS proteins. | 35 |
| 28808085 | 2017 | Sub-mitochondrial localization of the genetic-tagged mitochondrial intermembrane space-bridging components Mic19, Mic60 and Sam50. | 17 |
| 28808085 | 2017 | Sub-mitochondrial localization of the genetic-tagged mitochondrial intermembrane space-bridging components Mic19, Mic60 and Sam50. | 17 |
| 26416881 | 2015 | The Oxidation Status of Mic19 Regulates MICOS Assembly. | 20 |
| 26416881 | 2015 | The Oxidation Status of Mic19 Regulates MICOS Assembly. | 20 |
| 23019327 | 2012 | Targeting and import mechanism of coiled-coil helix coiled-coil helix domain-containing protein 3 (ChChd3) into the mitochondrial intermembrane space. | 35 |
| 23019327 | 2012 | Targeting and import mechanism of coiled-coil helix coiled-coil helix domain-containing protein 3 (ChChd3) into the mitochondrial intermembrane space. | 35 |
| 21081504 | 2011 | ChChd3, an inner mitochondrial membrane protein, is essential for maintaining crista integrity and mitochondrial function. | 157 |
| 21081504 | 2011 | ChChd3, an inner mitochondrial membrane protein, is essential for maintaining crista integrity and mitochondrial function. | 157 |
| 20379614 | 2010 | Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. | 78 |
| 20877624 | 2010 | Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression. | 20 |
| 20379614 | 2010 | Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. | 78 |
Citation
Dessen P
CHCHD3 (coiled-coil-helix-coiled-coil-helix domain containing 3)
Atlas Genet Cytogenet Oncol Haematol. 2014-08-01
Online version: http://atlasgeneticsoncology.org/gene/54214/chchd3-(coiled-coil-helix-coiled-coil-helix-domain-containing-3)
