Identity
HGNC
LOCATION
3q21.3
LOCUSID
ALIAS
CHCM1,MICOS25,Mic25,PPP1R23
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 84303
MIM: 615634
HGNC: 28184
Ensembl: ENSG00000159685
Variants:
dbSNP: 84303
ClinVar: 84303
TCGA: ENSG00000159685
COSMIC: CHCHD6
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000159685 | ENST00000290913 | Q9BRQ6 |
| ENSG00000159685 | ENST00000503119 | J3QTB2 |
| ENSG00000159685 | ENST00000508789 | J3QTA6 |
| ENSG00000159685 | ENST00000513253 | H0Y922 |
Expression (GTEx)
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 36104602 | 2022 | A CHCHD6-APP axis connects amyloid and mitochondrial pathology in Alzheimer's disease. | 0 |
| 36104602 | 2022 | A CHCHD6-APP axis connects amyloid and mitochondrial pathology in Alzheimer's disease. | 0 |
| 26530328 | 2015 | Mitofilin and CHCHD6 physically interact with Sam50 to sustain cristae structure. | 53 |
| 26530328 | 2015 | Mitofilin and CHCHD6 physically interact with Sam50 to sustain cristae structure. | 53 |
| 22228767 | 2012 | CHCM1/CHCHD6, novel mitochondrial protein linked to regulation of mitofilin and mitochondrial cristae morphology. | 55 |
| 22228767 | 2012 | CHCM1/CHCHD6, novel mitochondrial protein linked to regulation of mitofilin and mitochondrial cristae morphology. | 55 |
| 20379614 | 2010 | Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. | 78 |
| 20379614 | 2010 | Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. | 78 |
| 19240061 | 2009 | Coeliac disease-associated risk variants in TNFAIP3 and REL implicate altered NF-kappaB signalling. | 94 |
| 19240061 | 2009 | Coeliac disease-associated risk variants in TNFAIP3 and REL implicate altered NF-kappaB signalling. | 94 |
| 17624330 | 2007 | The mitochondrial inner membrane protein mitofilin exists as a complex with SAM50, metaxins 1 and 2, coiled-coil-helix coiled-coil-helix domain-containing protein 3 and 6 and DnaJC11. | 87 |
| 17624330 | 2007 | The mitochondrial inner membrane protein mitofilin exists as a complex with SAM50, metaxins 1 and 2, coiled-coil-helix coiled-coil-helix domain-containing protein 3 and 6 and DnaJC11. | 87 |
Citation
Dessen P
CHCHD6 (coiled-coil-helix-coiled-coil-helix domain containing 6)
Atlas Genet Cytogenet Oncol Haematol. 2014-08-01
Online version: http://atlasgeneticsoncology.org/gene/54215/chchd6-(coiled-coil-helix-coiled-coil-helix-domain-containing-6)
