CLIP2 (CAP-Gly domain containing linker protein 2)

2014-08-01 Affiliation

Identity

HGNC

CLIP2

LOCATION

7q11.23

LOCUSID

7461

ALIAS

CLIP,CLIP-115,CYLN2,WBSCR3,WBSCR4,WSCR3,WSCR4

FUSION GENES

Show Gene Fusions

Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool

Other Information

Locus ID:

NCBI: 7461
MIM: 603432
HGNC: 2586
Ensembl: ENSG00000106665

Variants:

dbSNP: 7461
ClinVar: 7461
TCGA: ENSG00000106665
COSMIC: CLIP2

RNA/Proteins

Gene ID	Transcript ID	Uniprot
ENSG00000106665	ENST00000223398	Q9UDT6
ENSG00000106665	ENST00000361545	Q9UDT6
ENSG00000106665	ENST00000487447	H7C5H8
ENSG00000106665	ENST00000493166	H7C4L6

Expression (GTEx)

100

150

Adipose - Subcutaneous

Adipose - Visceral

Adrenal Gland

Artery - Aorta

Artery - Tibial

Bladder

Brain - Amygdala

Brain - Anterior cingulate cortex

Brain - Caudate

Brain - Cerebellar Hemisphere

Brain - Cerebellum

Brain - Cortex

Brain - Frontal Cortex

Brain - Hippocampus

Brain - Hypothalamus

Brain - Nucleus accumbens

Brain - Putamen

Brain - Spinal cord

Brain - Substantia nigra

Breast - Mammary Tissue

Cells - Cultured fibroblasts

Cells - EBV - transformed lymphocytes

Cervix - Ectocervix

Cervix - Endocervix

Colon - Sigmoid

Colon - Transverse

Esophagus - Gastroesophageal Junction

Esophagus - Mucosa

Esophagus - Muscularis

Fallopian Tube

Heart - Atrial Appendage

Heart - Left Ventricle

Kidney - Cortex

Kidney - Medulla

Liver

Lung

Minor Salivary Gland

Muscle - Skeletal

Nerve - Tibial

Ovary

Pancreas

Pituitary

Prostate

Skin - Not Sun Exposed

Skin - Sun Exposed

Small Intestine - Terminal Ileum

Spleen

Stomach

Testis

Thyroid

Uterus

Vagina

Whole Blood

Protein levels (Protein atlas)

Not detected

Low

Medium

High

References

Pubmed ID	Year	Title	Citations
38650040	2024	Clinical, pathologic, and genomic characteristics of two pediatric glioneuronal tumors with a CLIP2::MET fusion.	0
38650040	2024	Clinical, pathologic, and genomic characteristics of two pediatric glioneuronal tumors with a CLIP2::MET fusion.	0
32734598	2021	Whole exome sequencing identifies three novel gene mutations in patients with the triad of diabetic ketoacidosis, hypertriglyceridemia, and acute pancreatitis.	6
32734598	2021	Whole exome sequencing identifies three novel gene mutations in patients with the triad of diabetic ketoacidosis, hypertriglyceridemia, and acute pancreatitis.	6
30896018	2019	CILP-2 is a novel secreted protein and associated with insulin resistance.	13
30896018	2019	CILP-2 is a novel secreted protein and associated with insulin resistance.	13
27729373	2016	Integration of a radiation biomarker into modeling of thyroid carcinogenesis and post-Chernobyl risk assessment.	12
27729373	2016	Integration of a radiation biomarker into modeling of thyroid carcinogenesis and post-Chernobyl risk assessment.	12
25284583	2015	CLIP2 as radiation biomarker in papillary thyroid carcinoma.	22
25957251	2015	Dose-dependent expression of CLIP2 in post-Chernobyl papillary thyroid carcinomas.	13
25284583	2015	CLIP2 as radiation biomarker in papillary thyroid carcinoma.	22
25957251	2015	Dose-dependent expression of CLIP2 in post-Chernobyl papillary thyroid carcinomas.	13
22608712	2012	The contribution of CLIP2 haploinsufficiency to the clinical manifestations of the Williams-Beuren syndrome.	16
22608712	2012	The contribution of CLIP2 haploinsufficiency to the clinical manifestations of the Williams-Beuren syndrome.	16
21606360	2011	Gain of chromosome band 7q11 in papillary thyroid carcinomas of young patients is associated with exposure to low-dose irradiation.	32

Citation

Dessen P

CLIP2 (CAP-Gly domain containing linker protein 2)

Atlas Genet Cytogenet Oncol Haematol. 2014-08-01

Online version: http://atlasgeneticsoncology.org/gene/54218/clip2-(cap-gly-domain-containing-linker-protein-2)