CMTR1 (cap methyltransferase 1)

2014-08-01  

Identity

HGNC
LOCATION
6p21.2
LOCUSID
ALIAS
FTSJD2,KIAA0082,MTr1,hMTr1
FUSION GENES

Other Information

Locus ID:

NCBI: 23070
MIM: 616189
HGNC: 21077
Ensembl: ENSG00000137200

Variants:

dbSNP: 23070
ClinVar: 23070
TCGA: ENSG00000137200
COSMIC: CMTR1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000137200ENST00000373451Q8N1G2
ENSG00000137200ENST00000455891Q5T7F5
ENSG00000137200ENST00000457419H0Y4T0
ENSG00000137200ENST00000475364H0YCQ1

Expression (GTEx)

0
50
100
150

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
370244652023CMTR1 promotes colorectal cancer cell growth and immune evasion by transcriptionally regulating STAT3.2
370244652023CMTR1 promotes colorectal cancer cell growth and immune evasion by transcriptionally regulating STAT3.2
324045102020The mRNA Cap 2'-O-Methyltransferase CMTR1 Regulates the Expression of Certain Interferon-Stimulated Genes.27
324045102020The mRNA Cap 2'-O-Methyltransferase CMTR1 Regulates the Expression of Certain Interferon-Stimulated Genes.27
303209102019Interactome analysis of the human Cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 1 (hMTr1) protein.2
303209102019Interactome analysis of the human Cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 1 (hMTr1) protein.2
303970982018Human RNA cap1 methyltransferase CMTr1 cooperates with RNA helicase DHX15 to modify RNAs with highly structured 5' termini.11
303970982018Human RNA cap1 methyltransferase CMTr1 cooperates with RNA helicase DHX15 to modify RNAs with highly structured 5' termini.11
289716292017Regulation and function of CMTR1-dependent mRNA cap methylation.17
289716292017Regulation and function of CMTR1-dependent mRNA cap methylation.17
244024422014Structural analysis of human 2'-O-ribose methyltransferases involved in mRNA cap structure formation.49
244024422014Structural analysis of human 2'-O-ribose methyltransferases involved in mRNA cap structure formation.49
207133562010Characterization of hMTr1, a human Cap1 2'-O-ribose methyltransferase.85
207133562010Characterization of hMTr1, a human Cap1 2'-O-ribose methyltransferase.85
185331092008The human interferon-regulated ISG95 protein interacts with RNA polymerase II and shows methyltransferase activity.25

Citation

Dessen P

CMTR1 (cap methyltransferase 1)

Atlas Genet Cytogenet Oncol Haematol. 2014-08-01

Online version: http://atlasgeneticsoncology.org/gene/54223/cmtr1-(cap-methyltransferase-1)