Identity
HGNC
LOCATION
20p12.3
LOCUSID
ALIAS
C20orf155,CLS,CLS1,GCD10,dJ967N21.6
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 54675
MIM: 608188
HGNC: 16148
Ensembl: ENSG00000088766
Variants:
dbSNP: 54675
ClinVar: 54675
TCGA: ENSG00000088766
COSMIC: CRLS1
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000088766 | ENST00000378863 | Q9UJA2 |
| ENSG00000088766 | ENST00000378868 | Q9UJA2 |
| ENSG00000088766 | ENST00000452938 | Q6NTG3 |
Expression (GTEx)
Pathways
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 35147173 | 2022 | Deleterious variants in CRLS1 lead to cardiolipin deficiency and cause an autosomal recessive multi-system mitochondrial disease. | 11 |
| 35147173 | 2022 | Deleterious variants in CRLS1 lead to cardiolipin deficiency and cause an autosomal recessive multi-system mitochondrial disease. | 11 |
| 34099597 | 2021 | LINC01272 Suppressed Cell Multiplication and Induced Apoptosis Via Regulating MiR-7-5p/CRLS1 Axis in Lung Cancer. | 7 |
| 34099597 | 2021 | LINC01272 Suppressed Cell Multiplication and Induced Apoptosis Via Regulating MiR-7-5p/CRLS1 Axis in Lung Cancer. | 7 |
| 30825207 | 2019 | Small regulatory polypeptide of amino acid response negatively relates to poor prognosis and controls hepatocellular carcinoma progression via regulating microRNA-5581-3p/human cardiolipin synthase 1. | 7 |
| 30825207 | 2019 | Small regulatory polypeptide of amino acid response negatively relates to poor prognosis and controls hepatocellular carcinoma progression via regulating microRNA-5581-3p/human cardiolipin synthase 1. | 7 |
| 29251771 | 2018 | Inactivation of cardiolipin synthase triggers changes in mitochondrial morphology. | 12 |
| 29251771 | 2018 | Inactivation of cardiolipin synthase triggers changes in mitochondrial morphology. | 12 |
| 22584571 | 2012 | Myocardial regulation of lipidomic flux by cardiolipin synthase: setting the beat for bioenergetic efficiency. | 22 |
| 22584571 | 2012 | Myocardial regulation of lipidomic flux by cardiolipin synthase: setting the beat for bioenergetic efficiency. | 22 |
| 20652826 | 2011 | Cardiolipin synthase-1 mRNA expression does not correlate with endogenous cardiolipin synthase enzyme activity in vitro and in vivo in mammalian lipopolysaccharide models of inflammation. | 2 |
| 20652826 | 2011 | Cardiolipin synthase-1 mRNA expression does not correlate with endogenous cardiolipin synthase enzyme activity in vitro and in vivo in mammalian lipopolysaccharide models of inflammation. | 2 |
| 20877624 | 2010 | Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression. | 20 |
| 20877624 | 2010 | Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression. | 20 |
| 19048414 | 2009 | Renal involvement in the antiphospholipid syndrome (APS)-APS nephropathy. | 25 |
Citation
Dessen P
CRLS1 (cardiolipin synthase 1)
Atlas Genet Cytogenet Oncol Haematol. 2014-08-01
Online version: http://atlasgeneticsoncology.org/gene/54238/crls1-(cardiolipin-synthase-1)
