DCAF8 (DDB1 and CUL4 associated factor 8)

2014-08-01  

Identity

HGNC
DCAF8
LOCATION
1q23.2
LOCUSID
50717
ALIAS
GAN2,H326,WDR42A
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 50717
MIM: 615820
HGNC: 24891
Ensembl: ENSG00000132716

Variants:

dbSNP: 50717
ClinVar: 50717
TCGA: ENSG00000132716
COSMIC: DCAF8

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000132716ENST00000326837Q5TAQ9
ENSG00000132716ENST00000368073Q5TAQ9
ENSG00000132716ENST00000368074Q5TAQ9
ENSG00000132716ENST00000407642Q5TAQ7
ENSG00000132716ENST00000419626Q5TAQ6
ENSG00000132716ENST00000440682Q5TAQ5
ENSG00000132716ENST00000447377Q5TAQ8
ENSG00000132716ENST00000461888V9GY54
ENSG00000132716ENST00000473382V9GY98
ENSG00000132716ENST00000475733Q5TAQ9
ENSG00000132716ENST00000477163V9GZ39
ENSG00000132716ENST00000490368V9GYZ9
ENSG00000132716ENST00000495887V9GYQ9
ENSG00000132716ENST00000610139Q5TAQ9

Expression (GTEx)

0
50
100
150
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
245006462014Ubiquitin ligase defect by DCAF8 mutation causes HMSN2 with giant axons.7
214247322011Host cell targets of tegument protein VP22 of herpes simplex virus 1.4
225009892012Characterization of nuclear import and export signals determining the subcellular localization of WD repeat-containing protein 42A (WDR42A).2

Citation

Dessen P

DCAF8 (DDB1 and CUL4 associated factor 8)

Atlas Genet Cytogenet Oncol Haematol. 2014-08-01

Online version: http://atlasgeneticsoncology.org/gene/54249/dcaf8-(ddb1-and-cul4-associated-factor-8)