Identity
HGNC
LOCATION
17p13.1
LOCUSID
ALIAS
MRD62,PSD95,SAP-90,SAP90
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 1742
MIM: 602887
HGNC: 2903
Ensembl: ENSG00000132535
Variants:
dbSNP: 1742
ClinVar: 1742
TCGA: ENSG00000132535
COSMIC: DLG4
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38427737 | 2024 | Targeting postsynaptic glutamate receptor scaffolding proteins PSD-95 and PICK1 for obesity treatment. | 0 |
| 38427737 | 2024 | Targeting postsynaptic glutamate receptor scaffolding proteins PSD-95 and PICK1 for obesity treatment. | 0 |
| 36732356 | 2023 | FMRP, FXR1 protein and Dlg4 mRNA, which are associated with fragile X syndrome, are involved in the ubiquitin-proteasome system. | 2 |
| 37891164 | 2023 | Multivalent Tau/PSD-95 interactions arrest in vitro condensates and clusters mimicking the postsynaptic density. | 3 |
| 36732356 | 2023 | FMRP, FXR1 protein and Dlg4 mRNA, which are associated with fragile X syndrome, are involved in the ubiquitin-proteasome system. | 2 |
| 37891164 | 2023 | Multivalent Tau/PSD-95 interactions arrest in vitro condensates and clusters mimicking the postsynaptic density. | 3 |
| 35457207 | 2022 | Neurodevelopmental Disorders Associated with PSD-95 and Its Interaction Partners. | 15 |
| 35461266 | 2022 | Increased levels of the synaptic proteins PSD-95, SNAP-25, and neurogranin in the cerebrospinal fluid of patients with Alzheimer's disease. | 20 |
| 35457207 | 2022 | Neurodevelopmental Disorders Associated with PSD-95 and Its Interaction Partners. | 15 |
| 35461266 | 2022 | Increased levels of the synaptic proteins PSD-95, SNAP-25, and neurogranin in the cerebrospinal fluid of patients with Alzheimer's disease. | 20 |
| 33597769 | 2021 | DLG4-related synaptopathy: a new rare brain disorder. | 14 |
| 33794133 | 2021 | Interaction between the guanylate kinase domain of PSD-95 and the proline-rich region and microtubule binding repeats 2 and 3 of tau. | 4 |
| 34538002 | 2021 | Zinc-chelating postsynaptic density-95 N-terminus impairs its palmitoyl modification. | 2 |
| 34830481 | 2021 | PSD-95: An Effective Target for Stroke Therapy Using Neuroprotective Peptides. | 15 |
| 34884918 | 2021 | Heat Shock Factor 1 Directly Regulates Postsynaptic Scaffolding PSD-95 in Aging and Huntington's Disease and Influences Striatal Synaptic Density. | 7 |
Citation
Dessen P
DLG4 (discs large MAGUK scaffold protein 4)
Atlas Genet Cytogenet Oncol Haematol. 2014-08-01
Online version: http://atlasgeneticsoncology.org/gene/54255/dlg4-(discs-large-maguk-scaffold-protein-4)
