Identity
HGNC
LOCATION
20q11.23
LOCUSID
ALIAS
DAP-4,DAP4,DLP4,SAPAP-4,SAPAP4
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 22839
MIM: 616191
HGNC: 24476
Ensembl: ENSG00000080845
Variants:
dbSNP: 22839
ClinVar: 22839
TCGA: ENSG00000080845
COSMIC: DLGAP4
RNA/Proteins
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Neuronal System | REACTOME | R-HSA-112316 |
| Protein-protein interactions at synapses | REACTOME | R-HSA-6794362 |
| Interactions of neurexins and neuroligins at synapses | REACTOME | R-HSA-6794361 |
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37822284 | 2024 | CircDLGAP4 overexpression ameliorates neuronal injury in Parkinson's disease by binding to EIF4A3 and increasing HMGA2 expression. | 0 |
| 37822284 | 2024 | CircDLGAP4 overexpression ameliorates neuronal injury in Parkinson's disease by binding to EIF4A3 and increasing HMGA2 expression. | 0 |
| 37615249 | 2023 | CircDLGAP4 induces autophagy and improves endothelial cell dysfunction in atherosclerosis by targeting PTPN4 with miR-134-5p. | 1 |
| 37615249 | 2023 | CircDLGAP4 induces autophagy and improves endothelial cell dysfunction in atherosclerosis by targeting PTPN4 with miR-134-5p. | 1 |
| 36396671 | 2022 | DLGAP4 acts as an effective prognostic predictor for hepatocellular carcinoma and is closely related to tumour progression. | 2 |
| 36396671 | 2022 | DLGAP4 acts as an effective prognostic predictor for hepatocellular carcinoma and is closely related to tumour progression. | 2 |
| 33230102 | 2020 | Exosomal circ_DLGAP4 promotes diabetic kidney disease progression by sponging miR-143 and targeting ERBB3/NF-κB/MMP-2 axis. | 36 |
| 33230102 | 2020 | Exosomal circ_DLGAP4 promotes diabetic kidney disease progression by sponging miR-143 and targeting ERBB3/NF-κB/MMP-2 axis. | 36 |
| 24986922 | 2014 | Epigenetic remodelling and dysregulation of DLGAP4 is linked with early-onset cerebellar ataxia. | 16 |
| 24986922 | 2014 | Epigenetic remodelling and dysregulation of DLGAP4 is linked with early-onset cerebellar ataxia. | 16 |
| 19086053 | 2009 | Identification of new putative susceptibility genes for several psychiatric disorders by association analysis of regulatory and non-synonymous SNPs of 306 genes involved in neurotransmission and neurodevelopment. | 39 |
| 19086053 | 2009 | Identification of new putative susceptibility genes for several psychiatric disorders by association analysis of regulatory and non-synonymous SNPs of 306 genes involved in neurotransmission and neurodevelopment. | 39 |
| 10521485 | 1999 | nArgBP2, a novel neural member of ponsin/ArgBP2/vinexin family that interacts with synapse-associated protein 90/postsynaptic density-95-associated protein (SAPAP). | 29 |
| 10521485 | 1999 | nArgBP2, a novel neural member of ponsin/ArgBP2/vinexin family that interacts with synapse-associated protein 90/postsynaptic density-95-associated protein (SAPAP). | 29 |
| 9115257 | 1997 | SAPAPs. A family of PSD-95/SAP90-associated proteins localized at postsynaptic density. | 121 |
Citation
Dessen P
DLGAP4 (DLG associated protein 4)
Atlas Genet Cytogenet Oncol Haematol. 2014-08-01
Online version: http://atlasgeneticsoncology.org/gene/54256/dlgap4-(dlg-associated-protein-4)
