DNM3 (dynamin 3)

2014-08-01  

Identity

HGNC
LOCATION
1q24.3
LOCUSID
ALIAS
Dyna
FUSION GENES

Other Information

Locus ID:

NCBI: 26052
MIM: 611445
HGNC: 29125
Ensembl: ENSG00000197959

Variants:

dbSNP: 26052
ClinVar: 26052
TCGA: ENSG00000197959
COSMIC: DNM3

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000197959ENST00000355305Q9UQ16
ENSG00000197959ENST00000367731Q9UQ16
ENSG00000197959ENST00000367733Q9UQ16
ENSG00000197959ENST00000485254H0YBC6
ENSG00000197959ENST00000520906E5RHK8
ENSG00000197959ENST00000523513E5RIK2
ENSG00000197959ENST00000627582Q9UQ16

Expression (GTEx)

0
10
20
30
40
50
60
70

Pathways

PathwaySourceExternal ID
EndocytosisKEGGko04144
EndocytosisKEGGhsa04144
Bacterial invasion of epithelial cellsKEGGko05100
Bacterial invasion of epithelial cellsKEGGhsa05100
Endocrine and other factor-regulated calcium reabsorptionKEGGko04961
Endocrine and other factor-regulated calcium reabsorptionKEGGhsa04961
Synaptic vesicle cycleKEGGko04721
Synaptic vesicle cycleKEGGhsa04721
Immune SystemREACTOMER-HSA-168256
Adaptive Immune SystemREACTOMER-HSA-1280218
MHC class II antigen presentationREACTOMER-HSA-2132295
Innate Immune SystemREACTOMER-HSA-168249
Toll-Like Receptors CascadesREACTOMER-HSA-168898
Toll Like Receptor 4 (TLR4) CascadeREACTOMER-HSA-166016
Signal TransductionREACTOMER-HSA-162582
Signalling by NGFREACTOMER-HSA-166520
NGF signalling via TRKA from the plasma membraneREACTOMER-HSA-187037
Retrograde neurotrophin signallingREACTOMER-HSA-177504
Vesicle-mediated transportREACTOMER-HSA-5653656
Membrane TraffickingREACTOMER-HSA-199991
Developmental BiologyREACTOMER-HSA-1266738
Axon guidanceREACTOMER-HSA-422475
L1CAM interactionsREACTOMER-HSA-373760
Recycling pathway of L1REACTOMER-HSA-437239
Phospholipase D signaling pathwayKEGGko04072
Phospholipase D signaling pathwayKEGGhsa04072
Clathrin-mediated endocytosisREACTOMER-HSA-8856828

References

Pubmed IDYearTitleCitations
365286672022Integrated multi-omic analysis of low-grade ovarian serous carcinoma collected from short and long-term survivors.3
365286672022Integrated multi-omic analysis of low-grade ovarian serous carcinoma collected from short and long-term survivors.3
328734362021Analysis of DNM3 and VAMP4 as genetic modifiers of LRRK2 Parkinson's disease.9
336228742021TBX15 rs98422, DNM3 rs1011731, RAD51B rs8017304, and rs2588809 Gene Polymorphisms and Associations With Pituitary Adenoma.1
328734362021Analysis of DNM3 and VAMP4 as genetic modifiers of LRRK2 Parkinson's disease.9
336228742021TBX15 rs98422, DNM3 rs1011731, RAD51B rs8017304, and rs2588809 Gene Polymorphisms and Associations With Pituitary Adenoma.1
325735162020The Expression of Dynamin 1, 2, and 3 in Human Hepatocellular Carcinoma and Patient Prognosis.4
325735162020The Expression of Dynamin 1, 2, and 3 in Human Hepatocellular Carcinoma and Patient Prognosis.4
301330892019No association of DNM3 with age of onset in Asian Parkinson's disease.2
303407922019No evidence for DNM3 as genetic modifier of age at onset in idiopathic Parkinson's disease.0
301330892019No association of DNM3 with age of onset in Asian Parkinson's disease.2
303407922019No evidence for DNM3 as genetic modifier of age at onset in idiopathic Parkinson's disease.0
278374352017Exosomal miR-221 targets DNM3 to induce tumor progression and temozolomide resistance in glioma.62
278374352017Exosomal miR-221 targets DNM3 to induce tumor progression and temozolomide resistance in glioma.62
267843882016DNM3 Attenuates Hepatocellular Carcinoma Growth by Activating P53.22

Citation

Dessen P

DNM3 (dynamin 3)

Atlas Genet Cytogenet Oncol Haematol. 2014-08-01

Online version: http://atlasgeneticsoncology.org/gene/54259/dnm3-(dynamin-3)