Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 80005
MIM: 616904
HGNC: 23476
Ensembl: ENSG00000147459
Variants:
dbSNP: 80005
ClinVar: 80005
TCGA: ENSG00000147459
COSMIC: DOCK5
RNA/Proteins
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Hemostasis | REACTOME | R-HSA-109582 |
| Factors involved in megakaryocyte development and platelet production | REACTOME | R-HSA-983231 |
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38161229 | 2024 | Dock5 Deficiency Promotes Proteinuric Kidney Diseases via Modulating Podocyte Lipid Metabolism. | 1 |
| 38161229 | 2024 | Dock5 Deficiency Promotes Proteinuric Kidney Diseases via Modulating Podocyte Lipid Metabolism. | 1 |
| 37434235 | 2023 | PHF5A regulates the expression of the DOCK5 variant to promote HNSCC progression through p38 MAPK activation. | 2 |
| 37434235 | 2023 | PHF5A regulates the expression of the DOCK5 variant to promote HNSCC progression through p38 MAPK activation. | 2 |
| 32920599 | 2021 | Positional cloning and comprehensive mutation analysis of a Japanese family with lithium-responsive bipolar disorder identifies a novel DOCK5 mutation. | 3 |
| 34216686 | 2021 | ZEB1 represses biogenesis of circ-DOCK5 to facilitate metastasis in esophageal squamous cell carcinoma via a positive feedback loop with TGF-β. | 19 |
| 32920599 | 2021 | Positional cloning and comprehensive mutation analysis of a Japanese family with lithium-responsive bipolar disorder identifies a novel DOCK5 mutation. | 3 |
| 34216686 | 2021 | ZEB1 represses biogenesis of circ-DOCK5 to facilitate metastasis in esophageal squamous cell carcinoma via a positive feedback loop with TGF-β. | 19 |
| 29945995 | 2018 | Characterization of Alternative Splicing Events in HPV-Negative Head and Neck Squamous Cell Carcinoma Identifies an Oncogenic DOCK5 Variant. | 21 |
| 29945995 | 2018 | Characterization of Alternative Splicing Events in HPV-Negative Head and Neck Squamous Cell Carcinoma Identifies an Oncogenic DOCK5 Variant. | 21 |
| 27669437 | 2017 | The focal adhesion-associated proteins DOCK5 and GIT2 comprise a rheostat in control of epithelial invasion. | 19 |
| 29089502 | 2017 | Allosteric inhibition of the guanine nucleotide exchange factor DOCK5 by a small molecule. | 13 |
| 27669437 | 2017 | The focal adhesion-associated proteins DOCK5 and GIT2 comprise a rheostat in control of epithelial invasion. | 19 |
| 29089502 | 2017 | Allosteric inhibition of the guanine nucleotide exchange factor DOCK5 by a small molecule. | 13 |
| 22595969 | 2012 | Novel association approach for variable number tandem repeats (VNTRs) identifies DOCK5 as a susceptibility gene for severe obesity. | 13 |
Citation
Dessen P
DOCK5 (dedicator of cytokinesis 5)
Atlas Genet Cytogenet Oncol Haematol. 2014-08-01
Online version: http://atlasgeneticsoncology.org/gene/54260/dock5-(dedicator-of-cytokinesis-5)
