Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 57572
MIM: 614194
HGNC: 19189
Ensembl: ENSG00000130158
Variants:
dbSNP: 57572
ClinVar: 57572
TCGA: ENSG00000130158
COSMIC: DOCK6
RNA/Proteins
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Hemostasis | REACTOME | R-HSA-109582 |
| Factors involved in megakaryocyte development and platelet production | REACTOME | R-HSA-983231 |
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 36601873 | 2023 | Associations of ANGPTL6, DOCK6, FABP1, and PCSK9 single-nucleotide variants with hypercholesterolemia in the Polish population: a cross-sectional study. | 0 |
| 36601873 | 2023 | Associations of ANGPTL6, DOCK6, FABP1, and PCSK9 single-nucleotide variants with hypercholesterolemia in the Polish population: a cross-sectional study. | 0 |
| 34742001 | 2022 | Overexpression of DOCK6 in oral squamous cell cancer promotes cellular migration and invasion and is associated with poor prognosis. | 2 |
| 35241069 | 2022 | Attenuated clinical and osteoclastic phenotypes of Paget's disease of bone linked to the p.Pro392Leu/SQSTM1 mutation by a rare variant in the DOCK6 gene. | 1 |
| 34742001 | 2022 | Overexpression of DOCK6 in oral squamous cell cancer promotes cellular migration and invasion and is associated with poor prognosis. | 2 |
| 35241069 | 2022 | Attenuated clinical and osteoclastic phenotypes of Paget's disease of bone linked to the p.Pro392Leu/SQSTM1 mutation by a rare variant in the DOCK6 gene. | 1 |
| 31654484 | 2020 | Expanding the phenotype in Adams-Oliver syndrome correlating with the genotype. | 4 |
| 31654484 | 2020 | Expanding the phenotype in Adams-Oliver syndrome correlating with the genotype. | 4 |
| 28287327 | 2019 | Mechanism of cell-intrinsic adaptation to Adams-Oliver Syndrome gene DOCK6 disruption highlights ubiquitin-like modifier ISG15 as a regulator of RHO GTPases. | 5 |
| 30898718 | 2019 | Novel compound heterozygous mutations of the DOCK6 gene in a familial case of Adams-Oliver syndrome 2. | 2 |
| 28287327 | 2019 | Mechanism of cell-intrinsic adaptation to Adams-Oliver Syndrome gene DOCK6 disruption highlights ubiquitin-like modifier ISG15 as a regulator of RHO GTPases. | 5 |
| 30898718 | 2019 | Novel compound heterozygous mutations of the DOCK6 gene in a familial case of Adams-Oliver syndrome 2. | 2 |
| 29587866 | 2018 | miR-148b-3p inhibits gastric cancer metastasis by inhibiting the Dock6/Rac1/Cdc42 axis. | 26 |
| 29587866 | 2018 | miR-148b-3p inhibits gastric cancer metastasis by inhibiting the Dock6/Rac1/Cdc42 axis. | 26 |
| 27693507 | 2016 | Cell-Intrinsic Adaptation Arising from Chronic Ablation of a Key Rho GTPase Regulator. | 26 |
Citation
Dessen P
DOCK6 (dedicator of cytokinesis 6)
Atlas Genet Cytogenet Oncol Haematol. 2014-08-01
Online version: http://atlasgeneticsoncology.org/gene/54261/dock6-(dedicator-of-cytokinesis-6)
