Identity
HGNC
LOCATION
16q22.1
LOCUSID
ALIAS
DUS2L,SMM1,URLC8
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 54920
MIM: 609707
HGNC: 26014
Ensembl: ENSG00000167264
Variants:
dbSNP: 54920
ClinVar: 54920
TCGA: ENSG00000167264
COSMIC: DUS2
RNA/Proteins
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Gene Expression | REACTOME | R-HSA-74160 |
| tRNA processing | REACTOME | R-HSA-72306 |
| tRNA modification in the nucleus and cytosol | REACTOME | R-HSA-6782315 |
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 30605527 | 2019 | Molecular basis for transfer RNA recognition by the double-stranded RNA-binding domain of human dihydrouridine synthase 2. | 14 |
| 30605527 | 2019 | Molecular basis for transfer RNA recognition by the double-stranded RNA-binding domain of human dihydrouridine synthase 2. | 14 |
| 26143927 | 2015 | From bacterial to human dihydrouridine synthase: automated structure determination. | 9 |
| 26429968 | 2015 | An extended dsRBD is required for post-transcriptional modification in human tRNAs. | 12 |
| 26143927 | 2015 | From bacterial to human dihydrouridine synthase: automated structure determination. | 9 |
| 26429968 | 2015 | An extended dsRBD is required for post-transcriptional modification in human tRNAs. | 12 |
| 22442237 | 2012 | Crystallization and preliminary X-ray crystallographic analysis of the catalytic domain of human dihydrouridine synthase. | 5 |
| 22442237 | 2012 | Crystallization and preliminary X-ray crystallographic analysis of the catalytic domain of human dihydrouridine synthase. | 5 |
| 20877624 | 2010 | Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression. | 20 |
| 20877624 | 2010 | Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression. | 20 |
| 18096616 | 2008 | Interaction of human tRNA-dihydrouridine synthase-2 with interferon-induced protein kinase PKR. | 20 |
| 18096616 | 2008 | Interaction of human tRNA-dihydrouridine synthase-2 with interferon-induced protein kinase PKR. | 20 |
Citation
Dessen P
DUS2 (dihydrouridine synthase 2)
Atlas Genet Cytogenet Oncol Haematol. 2014-08-01
Online version: http://atlasgeneticsoncology.org/gene/54269/dus2-(dihydrouridine-synthase-2)
