EHD1 (EH domain containing 1)

2014-08-01  

Identity

HGNC
LOCATION
11q13.1
LOCUSID
ALIAS
H-PAST,HPAST1,PAST,PAST1
FUSION GENES

Other Information

Locus ID:

NCBI: 10938
MIM: 605888
HGNC: 3242
Ensembl: ENSG00000110047

Variants:

dbSNP: 10938
ClinVar: 10938
TCGA: ENSG00000110047
COSMIC: EHD1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000110047ENST00000320631Q9H4M9
ENSG00000110047ENST00000320631B2R5U3
ENSG00000110047ENST00000359393Q9H4M9
ENSG00000110047ENST00000359393B2R5U3
ENSG00000110047ENST00000411683C9JIJ3
ENSG00000110047ENST00000421510C9J2Z4
ENSG00000110047ENST00000433803C9JC03
ENSG00000110047ENST00000455148C9JDQ8
ENSG00000110047ENST00000457202C9IZH1
ENSG00000110047ENST00000621096A0A024R571

Expression (GTEx)

0
50
100
150
200

Pathways

PathwaySourceExternal ID
EndocytosisKEGGko04144
EndocytosisKEGGhsa04144
HemostasisREACTOMER-HSA-109582
Factors involved in megakaryocyte development and platelet productionREACTOMER-HSA-983231

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
380116712024EHD1 impaired decidualization of endometrial stromal cells in recurrent implantation failure: role of SENP1 in modulating progesterone receptor signalling†.0
380116712024EHD1 impaired decidualization of endometrial stromal cells in recurrent implantation failure: role of SENP1 in modulating progesterone receptor signalling†.0
370749242023EHD1 promotes CP110 ubiquitination by centriolar satellite delivery of HERC2 to the mother centriole.7
374747602023EHD1-dependent traffic of IGF-1 receptor to the cell surface is essential for Ewing sarcoma tumorigenesis and metastasis.2
370749242023EHD1 promotes CP110 ubiquitination by centriolar satellite delivery of HERC2 to the mother centriole.7
374747602023EHD1-dependent traffic of IGF-1 receptor to the cell surface is essential for Ewing sarcoma tumorigenesis and metastasis.2
351495932022A Founder Mutation in EHD1 Presents with Tubular Proteinuria and Deafness.8
356161882022EHD1 promotes the cancer stem cell (CSC)-like traits of glioma cells via interacting with CD44 and suppressing CD44 degradation.3
351495932022A Founder Mutation in EHD1 Presents with Tubular Proteinuria and Deafness.8
356161882022EHD1 promotes the cancer stem cell (CSC)-like traits of glioma cells via interacting with CD44 and suppressing CD44 degradation.3
342177852021A feedback circuit comprising EHD1 and 14-3-3ζ sustains β-catenin/c-Myc-mediated aerobic glycolysis and proliferation in non-small cell lung cancer.8
342177852021A feedback circuit comprising EHD1 and 14-3-3ζ sustains β-catenin/c-Myc-mediated aerobic glycolysis and proliferation in non-small cell lung cancer.8
319324782020EHD1 and RUSC2 Control Basal Epidermal Growth Factor Receptor Cell Surface Expression and Recycling.6
321386152020EHD1 Modulates Cx43 Gap Junction Remodeling Associated With Cardiac Diseases.22
328003452020Identification of phostensin in association with Eps 15 homology domain-containing protein 1 (EHD1) and EHD4.0

Citation

Dessen P

EHD1 (EH domain containing 1)

Atlas Genet Cytogenet Oncol Haematol. 2014-08-01

Online version: http://atlasgeneticsoncology.org/gene/54277/ehd1-(eh-domain-containing-1)