Identity
HGNC
LOCATION
9q31.1
LOCUSID
ALIAS
PDIA10,TXNDC4
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 23071
MIM: 609170
HGNC: 18311
Ensembl: ENSG00000023318
Variants:
dbSNP: 23071
ClinVar: 23071
TCGA: ENSG00000023318
COSMIC: ERP44
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000023318 | ENST00000262455 | Q9BS26 |
| ENSG00000023318 | ENST00000262455 | A0A384MEE7 |
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Immune System | REACTOME | R-HSA-168256 |
| Innate Immune System | REACTOME | R-HSA-168249 |
| Neutrophil degranulation | REACTOME | R-HSA-6798695 |
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 34957576 | 2022 | Biogenesis of secretory immunoglobulin M requires intermediate non-native disulfide bonds and engagement of the protein disulfide isomerase ERp44. | 7 |
| 34957576 | 2022 | Biogenesis of secretory immunoglobulin M requires intermediate non-native disulfide bonds and engagement of the protein disulfide isomerase ERp44. | 7 |
| 34493236 | 2021 | Exosomal ERp44 derived from ER-stressed cells strengthens cisplatin resistance of nasopharyngeal carcinoma. | 18 |
| 34719307 | 2021 | Protein tyrosine phosphatase receptor type O (PTPRO) knockdown enhances the proliferative, invasive and angiogenic activities of trophoblast cells by suppressing ER resident protein 44 (ERp44) expression in preeclampsia. | 1 |
| 34493236 | 2021 | Exosomal ERp44 derived from ER-stressed cells strengthens cisplatin resistance of nasopharyngeal carcinoma. | 18 |
| 34719307 | 2021 | Protein tyrosine phosphatase receptor type O (PTPRO) knockdown enhances the proliferative, invasive and angiogenic activities of trophoblast cells by suppressing ER resident protein 44 (ERp44) expression in preeclampsia. | 1 |
| 32250737 | 2020 | The regulatory network of lncRNA DLX6-AS1/miR-149-5p/ERP44 is possibly related to the progression of preeclampsia. | 12 |
| 32250737 | 2020 | The regulatory network of lncRNA DLX6-AS1/miR-149-5p/ERP44 is possibly related to the progression of preeclampsia. | 12 |
| 30723194 | 2019 | Zinc regulates ERp44-dependent protein quality control in the early secretory pathway. | 27 |
| 30723194 | 2019 | Zinc regulates ERp44-dependent protein quality control in the early secretory pathway. | 27 |
| 27642162 | 2016 | Crystal Structure of the ERp44-Peroxiredoxin 4 Complex Reveals the Molecular Mechanisms of Thiol-Mediated Protein Retention. | 22 |
| 27642162 | 2016 | Crystal Structure of the ERp44-Peroxiredoxin 4 Complex Reveals the Molecular Mechanisms of Thiol-Mediated Protein Retention. | 22 |
| 24804790 | 2014 | MiR-101 regulates apoptosis of trophoblast HTR-8/SVneo cells by targeting endoplasmic reticulum (ER) protein 44 during preeclampsia. | 19 |
| 25097228 | 2014 | Progressive quality control of secretory proteins in the early secretory compartment by ERp44. | 19 |
| 25512553 | 2014 | GDM-associated insulin deficiency hinders the dissociation of SERT from ERp44 and down-regulates placental 5-HT uptake. | 21 |
Citation
Dessen P
ERP44 (endoplasmic reticulum protein 44)
Atlas Genet Cytogenet Oncol Haematol. 2014-08-01
Online version: http://atlasgeneticsoncology.org/gene/54289/erp44-(endoplasmic-reticulum-protein-44)
