EXOC7 (exocyst complex component 7)

2014-08-01  

Identity

HGNC
LOCATION
17q25.1
LOCUSID
ALIAS
2-5-3p,BLOM4,EX070,EXO70,EXOC1,Exo70p,NEDSEBA,YJL085W
FUSION GENES

Other Information

Locus ID:

NCBI: 23265
MIM: 608163
HGNC: 23214
Ensembl: ENSG00000182473

Variants:

dbSNP: 23265
ClinVar: 23265
TCGA: ENSG00000182473
COSMIC: EXOC7

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000182473ENST00000332065Q9UPT5
ENSG00000182473ENST00000335146Q9UPT5
ENSG00000182473ENST00000357231A0A0A0MRE1
ENSG00000182473ENST00000405575A0A0A0MSB8
ENSG00000182473ENST00000406660B5MCY9
ENSG00000182473ENST00000411744Q9UPT5
ENSG00000182473ENST00000420116C9JKC2
ENSG00000182473ENST00000442951C9JME6
ENSG00000182473ENST00000467929B4DJ07
ENSG00000182473ENST00000589210Q9UPT5
ENSG00000182473ENST00000589507K7ERQ5
ENSG00000182473ENST00000592559K7ENP8
ENSG00000182473ENST00000607838B4DJ07
ENSG00000182473ENST00000634349Q9UPT5

Expression (GTEx)

0
10
20
30
40
50
60
70
80
90

Pathways

PathwaySourceExternal ID
Insulin signaling pathwayKEGGko04910
Insulin signaling pathwayKEGGhsa04910
Metabolism of proteinsREACTOMER-HSA-392499
Peptide hormone metabolismREACTOMER-HSA-2980736
Insulin processingREACTOMER-HSA-264876
Organelle biogenesis and maintenanceREACTOMER-HSA-1852241
Cilium AssemblyREACTOMER-HSA-5617833
Cargo trafficking to the periciliary membraneREACTOMER-HSA-5620920
VxPx cargo-targeting to ciliumREACTOMER-HSA-5620916
Vesicle-mediated transportREACTOMER-HSA-5653656
Membrane TraffickingREACTOMER-HSA-199991
Translocation of GLUT4 to the plasma membraneREACTOMER-HSA-1445148

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
335422122021A fine balance between Prpf19 and Exoc7 in achieving degradation of aggregated protein and suppression of cell death in spinocerebellar ataxia type 3.5
337839952021Androgen receptor decreases renal cell carcinoma bone metastases via suppressing the osteolytic formation through altering a novel circEXOC7 regulatory axis.16
335422122021A fine balance between Prpf19 and Exoc7 in achieving degradation of aggregated protein and suppression of cell death in spinocerebellar ataxia type 3.5
337839952021Androgen receptor decreases renal cell carcinoma bone metastases via suppressing the osteolytic formation through altering a novel circEXOC7 regulatory axis.16
319132832020ULK1 phosphorylates Exo70 to suppress breast cancer metastasis.22
326584262020Appraising the Value of Serum and Serum-Derived Exosomal LncRNA-EXOC7 as a Promising Biomarker in Cervical Cancer.8
319132832020ULK1 phosphorylates Exo70 to suppress breast cancer metastasis.22
326584262020Appraising the Value of Serum and Serum-Derived Exosomal LncRNA-EXOC7 as a Promising Biomarker in Cervical Cancer.8
284899612019The role of Exo70 in exocytosis and beyond.11
309171192019Kinase suppressor of Ras 1 and Exo70 promote fatty acid-stimulated neurotensin secretion through ERK1/2 signaling.5
284899612019The role of Exo70 in exocytosis and beyond.11
309171192019Kinase suppressor of Ras 1 and Exo70 promote fatty acid-stimulated neurotensin secretion through ERK1/2 signaling.5
286985702017Exo70 is an independent prognostic factor in colon cancer.8
286985702017Exo70 is an independent prognostic factor in colon cancer.8
268488642016Exo70 is transcriptionally up-regulated by hepatic nuclear factor 4α and contributes to cell cycle control in hepatoma cells.4

Citation

Dessen P

EXOC7 (exocyst complex component 7)

Atlas Genet Cytogenet Oncol Haematol. 2014-08-01

Online version: http://atlasgeneticsoncology.org/gene/54294/exoc7-(exocyst-complex-component-7)