Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 144699
MIM: 609081
HGNC: 28624
Ensembl: ENSG00000171823
Variants:
dbSNP: 144699
ClinVar: 144699
TCGA: ENSG00000171823
COSMIC: FBXL14
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000171823 | ENST00000339235 | Q8N1E6 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 34285182 | 2021 | Loss of FBXL14 promotes mesenchymal shift and radioresistance of non-small cell lung cancer by TWIST1 stabilization. | 5 |
| 34285182 | 2021 | Loss of FBXL14 promotes mesenchymal shift and radioresistance of non-small cell lung cancer by TWIST1 stabilization. | 5 |
| 29348145 | 2018 | FBXL13 directs the proteolysis of CEP192 to regulate centrosome homeostasis and cell migration. | 13 |
| 29973690 | 2018 | FBXL14 abolishes breast cancer progression by targeting CDCP1 for proteasomal degradation. | 11 |
| 29348145 | 2018 | FBXL13 directs the proteolysis of CEP192 to regulate centrosome homeostasis and cell migration. | 13 |
| 29973690 | 2018 | FBXL14 abolishes breast cancer progression by targeting CDCP1 for proteasomal degradation. | 11 |
| 27923907 | 2017 | Deubiquitinase USP13 maintains glioblastoma stem cells by antagonizing FBXL14-mediated Myc ubiquitination. | 80 |
| 27923907 | 2017 | Deubiquitinase USP13 maintains glioblastoma stem cells by antagonizing FBXL14-mediated Myc ubiquitination. | 80 |
| 19955572 | 2010 | The hypoxia-controlled FBXL14 ubiquitin ligase targets SNAIL1 for proteasome degradation. | 89 |
| 19955572 | 2010 | The hypoxia-controlled FBXL14 ubiquitin ligase targets SNAIL1 for proteasome degradation. | 89 |
Citation
Dessen P
FBXL14 (F-box and leucine rich repeat protein 14)
Atlas Genet Cytogenet Oncol Haematol. 2014-08-01
Online version: http://atlasgeneticsoncology.org/gene/54313/gene-explorer/submit-meetings/
