GOLGB1 (golgin B1)

2014-08-01  

Identity

HGNC
LOCATION
3q13.33
LOCUSID
ALIAS
GCP,GCP372,GOLIM1
FUSION GENES

Other Information

Locus ID:

NCBI: 2804
MIM: 602500
HGNC: 4429
Ensembl: ENSG00000173230

Variants:

dbSNP: 2804
ClinVar: 2804
TCGA: ENSG00000173230
COSMIC: GOLGB1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000173230ENST00000340645Q14789
ENSG00000173230ENST00000393667Q14789
ENSG00000173230ENST00000472475C9J8Q0
ENSG00000173230ENST00000482512F8WF12
ENSG00000173230ENST00000489400H0Y867
ENSG00000173230ENST00000491690H7C5I7
ENSG00000173230ENST00000494517E7EU81
ENSG00000173230ENST00000614479Q14789

Expression (GTEx)

0
10
20
30
40
50
60

Pathways

PathwaySourceExternal ID
Metabolism of proteinsREACTOMER-HSA-392499
Post-translational protein modificationREACTOMER-HSA-597592
Asparagine N-linked glycosylationREACTOMER-HSA-446203
Transport to the Golgi and subsequent modificationREACTOMER-HSA-948021
ER to Golgi Anterograde TransportREACTOMER-HSA-199977
Vesicle-mediated transportREACTOMER-HSA-5653656
Membrane TraffickingREACTOMER-HSA-199991
trans-Golgi Network Vesicle BuddingREACTOMER-HSA-199992
Clathrin derived vesicle buddingREACTOMER-HSA-421837
Golgi Associated Vesicle BiogenesisREACTOMER-HSA-432722
COPI-mediated anterograde transportREACTOMER-HSA-6807878

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
294306282018Association between GOLGB1 tag-polymorphisms and nonsyndromic cleft palate only in the Brazilian population.1
304535272018Giantin Is Required for Post-Alcohol Recovery of Golgi in Liver Cells.12
294306282018Association between GOLGB1 tag-polymorphisms and nonsyndromic cleft palate only in the Brazilian population.1
304535272018Giantin Is Required for Post-Alcohol Recovery of Golgi in Liver Cells.12
287826252017Shifted Golgi targeting of glycosyltransferases and α-mannosidase IA from giantin to GM130-GRASP65 results in formation of high mannose N-glycans in aggressive prostate cancer cells.11
287826252017Shifted Golgi targeting of glycosyltransferases and α-mannosidase IA from giantin to GM130-GRASP65 results in formation of high mannose N-glycans in aggressive prostate cancer cells.11
266647862015Polymorphisms in three genes are associated with hemorrhagic stroke.5
266647862015Polymorphisms in three genes are associated with hemorrhagic stroke.5
250860692014Restoration of compact Golgi morphology in advanced prostate cancer enhances susceptibility to galectin-1-induced apoptosis by modifying mucin O-glycan synthesis.42
250860692014Restoration of compact Golgi morphology in advanced prostate cancer enhances susceptibility to galectin-1-induced apoptosis by modifying mucin O-glycan synthesis.42
234227532013Genetic mapping and exome sequencing identify 2 mutations associated with stroke protection in pediatric patients with sickle cell anemia.32
235557932013The golgin tether giantin regulates the secretory pathway by controlling stack organization within Golgi apparatus.41
240464482013A role for the Golgi matrix protein giantin in ciliogenesis through control of the localization of dynein-2.29
234227532013Genetic mapping and exome sequencing identify 2 mutations associated with stroke protection in pediatric patients with sickle cell anemia.32
235557932013The golgin tether giantin regulates the secretory pathway by controlling stack organization within Golgi apparatus.41

Citation

Dessen P

GOLGB1 (golgin B1)

Atlas Genet Cytogenet Oncol Haematol. 2014-08-01

Online version: http://atlasgeneticsoncology.org/gene/54336/golgb1-(golgin-b1)