GPR158 (G protein-coupled receptor 158)

2014-08-01  

Identity

HGNC
LOCATION
10p12.1
LOCUSID
ALIAS
-
FUSION GENES

Other Information

Locus ID:

NCBI: 57512
MIM: 614573
HGNC: 23689
Ensembl: ENSG00000151025

Variants:

dbSNP: 57512
ClinVar: 57512
TCGA: ENSG00000151025
COSMIC: GPR158

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000151025ENST00000376351Q5T848
ENSG00000151025ENST00000650135A0A3B3IUC3

Expression (GTEx)

0
10
20
30
40
50
60
70

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
369961982023Orphan receptor GPR158 serves as a metabotropic glycine receptor: mGlyR.9
369961982023Orphan receptor GPR158 serves as a metabotropic glycine receptor: mGlyR.9
347931982022Cryo-EM structure of human GPR158 receptor coupled to the RGS7-Gβ5 signaling complex.14
347931982022Cryo-EM structure of human GPR158 receptor coupled to the RGS7-Gβ5 signaling complex.14
348154012021Structure of the class C orphan GPCR GPR158 in complex with RGS7-Gβ5.8
348154012021Structure of the class C orphan GPCR GPR158 in complex with RGS7-Gβ5.8
308552002019GPR158 in the Visual System: Homeostatic Role in Regulation of Intraocular Pressure.3
311896662019Nonclassical Ligand-Independent Regulation of Go Protein by an Orphan Class C G-Protein-Coupled Receptor.6
315336542019Immunohistochemical validation of COL3A1, GPR158 and PITHD1 as prognostic biomarkers in early-stage ovarian carcinomas.28
308552002019GPR158 in the Visual System: Homeostatic Role in Regulation of Intraocular Pressure.3
311896662019Nonclassical Ligand-Independent Regulation of Go Protein by an Orphan Class C G-Protein-Coupled Receptor.6
315336542019Immunohistochemical validation of COL3A1, GPR158 and PITHD1 as prognostic biomarkers in early-stage ovarian carcinomas.28
294193762018Orphan receptor GPR158 controls stress-induced depression.36
294193762018Orphan receptor GPR158 controls stress-induced depression.36
284769312017A Genome-Wide Association Study Using a Custom Genotyping Array Identifies Variants in GPR158 Associated With Reduced Energy Expenditure in American Indians.25

Citation

Dessen P

GPR158 (G protein-coupled receptor 158)

Atlas Genet Cytogenet Oncol Haematol. 2014-08-01

Online version: http://atlasgeneticsoncology.org/gene/54344/new-content/gene-fusions-explorer/