Identity
HGNC
LOCATION
1p34.2
LOCUSID
ALIAS
HESR3,HEY3,HRT3,bHLHb33
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 26508
MIM: 609034
HGNC: 4882
Ensembl: ENSG00000163909
Variants:
dbSNP: 26508
ClinVar: 26508
TCGA: ENSG00000163909
COSMIC: HEYL
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000163909 | ENST00000372852 | Q9NQ87 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 36854682 | 2023 | Notch3 regulates Mybl2 via HeyL to limit proliferation and tumor initiation in breast cancer. | 3 |
| 37024320 | 2023 | Hypercoagulability evaluation in congenital red blood cell disorders using thrombin generation assay. | 0 |
| 36854682 | 2023 | Notch3 regulates Mybl2 via HeyL to limit proliferation and tumor initiation in breast cancer. | 3 |
| 37024320 | 2023 | Hypercoagulability evaluation in congenital red blood cell disorders using thrombin generation assay. | 0 |
| 35655915 | 2022 | Partial-Methylated HeyL Promoter Predicts the Severe Illness in Egyptian COVID-19 Patients. | 0 |
| 35655915 | 2022 | Partial-Methylated HeyL Promoter Predicts the Severe Illness in Egyptian COVID-19 Patients. | 0 |
| 34831437 | 2021 | The NOTCH3 Downstream Target HEYL Is Required for Efficient Human Airway Basal Cell Differentiation. | 4 |
| 34831437 | 2021 | The NOTCH3 Downstream Target HEYL Is Required for Efficient Human Airway Basal Cell Differentiation. | 4 |
| 31796022 | 2019 | The notch target gene HEYL modulates metastasis forming capacity of colorectal cancer patient-derived spheroid cells in vivo. | 13 |
| 31796022 | 2019 | The notch target gene HEYL modulates metastasis forming capacity of colorectal cancer patient-derived spheroid cells in vivo. | 13 |
| 28766235 | 2017 | Polymorphisms in Epithelial-Mesenchymal Transition-Related Genes and the Prognosis of Surgically Treated Non-small Cell Lung Cancer. | 5 |
| 28766235 | 2017 | Polymorphisms in Epithelial-Mesenchymal Transition-Related Genes and the Prognosis of Surgically Treated Non-small Cell Lung Cancer. | 5 |
| 27018646 | 2016 | LSD1 Mediates Neuronal Differentiation of Human Fetal Neural Stem Cells by Controlling the Expression of a Novel Target Gene, HEYL. | 32 |
| 27018646 | 2016 | LSD1 Mediates Neuronal Differentiation of Human Fetal Neural Stem Cells by Controlling the Expression of a Novel Target Gene, HEYL. | 32 |
| 25217524 | 2014 | The Notch pathway inhibits TGFβ signaling in breast cancer through HEYL-mediated crosstalk. | 17 |
Citation
Dessen P
HEYL (hes related family bHLH transcription factor with YRPW motif like)
Atlas Genet Cytogenet Oncol Haematol. 2014-08-01
Online version: http://atlasgeneticsoncology.org/gene/54359/heyl-(hes-related-family-bhlh-transcription-factor-with-yrpw-motif-like)
