Identity
HGNC
LOCATION
12q24.31
LOCUSID
ALIAS
HIP12,HIP3,ILWEQ
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 9026
MIM: 605613
HGNC: 18415
Ensembl: ENSG00000130787
Variants:
dbSNP: 9026
ClinVar: 9026
TCGA: ENSG00000130787
COSMIC: HIP1R
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000130787 | ENST00000253083 | O75146 |
| ENSG00000130787 | ENST00000535012 | H0YH66 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 36811277 | 2023 | DNA methylation and miR-92a-3p-mediated repression of HIP1R promotes pancreatic cancer progression by activating the PI3K/AKT pathway. | 1 |
| 36811277 | 2023 | DNA methylation and miR-92a-3p-mediated repression of HIP1R promotes pancreatic cancer progression by activating the PI3K/AKT pathway. | 1 |
| 35209947 | 2022 | Flurbiprofen inhibits cell proliferation in thyroid cancer through interrupting HIP1R-induced endocytosis of PTEN. | 4 |
| 35209947 | 2022 | Flurbiprofen inhibits cell proliferation in thyroid cancer through interrupting HIP1R-induced endocytosis of PTEN. | 4 |
| 32548851 | 2020 | HIP1R acts as a tumor suppressor in gastric cancer by promoting cancer cell apoptosis and inhibiting migration and invasion through modulating Akt. | 7 |
| 32548851 | 2020 | HIP1R acts as a tumor suppressor in gastric cancer by promoting cancer cell apoptosis and inhibiting migration and invasion through modulating Akt. | 7 |
| 30397328 | 2019 | HIP1R targets PD-L1 to lysosomal degradation to alter T cell-mediated cytotoxicity. | 117 |
| 31672988 | 2019 | Clathrin light chain A drives selective myosin VI recruitment to clathrin-coated pits under membrane tension. | 17 |
| 30397328 | 2019 | HIP1R targets PD-L1 to lysosomal degradation to alter T cell-mediated cytotoxicity. | 117 |
| 31672988 | 2019 | Clathrin light chain A drives selective myosin VI recruitment to clathrin-coated pits under membrane tension. | 17 |
| 26898757 | 2016 | The microRNA-23b/-27b cluster suppresses prostate cancer metastasis via Huntingtin-interacting protein 1-related. | 25 |
| 26898757 | 2016 | The microRNA-23b/-27b cluster suppresses prostate cancer metastasis via Huntingtin-interacting protein 1-related. | 25 |
| 25818163 | 2015 | The single nucleotide polymorphism Rs12817488 is associated with Parkinson's disease in the Chinese population. | 5 |
| 26341140 | 2015 | Low HIP1R mRNA and protein expression are associated with worse survival in diffuse large B-cell lymphoma patients treated with R-CHOP. | 7 |
| 25818163 | 2015 | The single nucleotide polymorphism Rs12817488 is associated with Parkinson's disease in the Chinese population. | 5 |
Citation
Dessen P
HIP1R (huntingtin interacting protein 1 related)
Atlas Genet Cytogenet Oncol Haematol. 2014-08-01
Online version: http://atlasgeneticsoncology.org/gene/54361/hip1r-(huntingtin-interacting-protein-1-related)
