Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 3354
MIM: 182132
HGNC: 5291
Ensembl: ENSG00000168830
Variants:
dbSNP: 3354
ClinVar: 3354
TCGA: ENSG00000168830
COSMIC: HTR1E
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000168830 | ENST00000305344 | P28566 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
PharmGKB
| Entity ID | Name | Type | Evidence | Association | PK | PD | PMIDs |
|---|---|---|---|---|---|---|---|
| PA172 | GNAI1 | Gene | Pathway | associated | 19741567 | ||
| PA173 | GNAI3 | Gene | Pathway | associated | 19741567 | ||
| PA24347 | GNAI2 | Gene | Pathway | associated | 19741567 |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 34093864 | 2021 | Serotonin/HTR1E signaling blocks chronic stress-promoted progression of ovarian cancer. | 14 |
| 34966948 | 2021 | Novel interaction between neurotrophic factor-α1/carboxypeptidase E and serotonin receptor, 5-HTR1E, protects human neurons against oxidative/neuroexcitotoxic stress via β-arrestin/ERK signaling. | 14 |
| 34093864 | 2021 | Serotonin/HTR1E signaling blocks chronic stress-promoted progression of ovarian cancer. | 14 |
| 34966948 | 2021 | Novel interaction between neurotrophic factor-α1/carboxypeptidase E and serotonin receptor, 5-HTR1E, protects human neurons against oxidative/neuroexcitotoxic stress via β-arrestin/ERK signaling. | 14 |
| 19455600 | 2010 | Association study of the serotoninergic system in migraine in the Spanish population. | 15 |
| 19455600 | 2010 | Association study of the serotoninergic system in migraine in the Spanish population. | 15 |
| 19058789 | 2009 | A common variant in DRD3 receptor is associated with autism spectrum disorder. | 31 |
| 19086053 | 2009 | Identification of new putative susceptibility genes for several psychiatric disorders by association analysis of regulatory and non-synonymous SNPs of 306 genes involved in neurotransmission and neurodevelopment. | 39 |
| 19156168 | 2009 | Pharmacogenetics of antipsychotic response in the CATIE trial: a candidate gene analysis. | 49 |
| 19058789 | 2009 | A common variant in DRD3 receptor is associated with autism spectrum disorder. | 31 |
| 19086053 | 2009 | Identification of new putative susceptibility genes for several psychiatric disorders by association analysis of regulatory and non-synonymous SNPs of 306 genes involved in neurotransmission and neurodevelopment. | 39 |
| 19156168 | 2009 | Pharmacogenetics of antipsychotic response in the CATIE trial: a candidate gene analysis. | 49 |
| 18079067 | 2008 | Genetic evaluation of the serotonergic system in chronic fatigue syndrome. | 30 |
| 18821565 | 2008 | Genome-wide association scan of quantitative traits for attention deficit hyperactivity disorder identifies novel associations and confirms candidate gene associations. | 154 |
| 18937842 | 2008 | The influence of serotonin- and other genes on impulsive behavioral aggression and cognitive impulsivity in children with attention-deficit/hyperactivity disorder (ADHD): Findings from a family-based association test (FBAT) analysis. | 76 |
Citation
Dessen P
HTR1E (5-hydroxytryptamine receptor 1E)
Atlas Genet Cytogenet Oncol Haematol. 2014-08-01
Online version: http://atlasgeneticsoncology.org/gene/54370/htr1e-(5-hydroxytryptamine-receptor-1e)
