Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 25998
MIM: 606457
HGNC: 17853
Ensembl: ENSG00000005700
Variants:
dbSNP: 25998
ClinVar: 25998
TCGA: ENSG00000005700
COSMIC: IBTK
RNA/Proteins
Expression (GTEx)
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 35216159 | 2022 | IBtkα Activates the β-Catenin-Dependent Transcription of MYC through Ubiquitylation and Proteasomal Degradation of GSK3β in Cancerous B Cells. | 6 |
| 35216159 | 2022 | IBtkα Activates the β-Catenin-Dependent Transcription of MYC through Ubiquitylation and Proteasomal Degradation of GSK3β in Cancerous B Cells. | 6 |
| 29317636 | 2018 | The expression of inhibitor of bruton's tyrosine kinase gene is progressively up regulated in the clinical course of chronic lymphocytic leukaemia conferring resistance to apoptosis. | 17 |
| 29317636 | 2018 | The expression of inhibitor of bruton's tyrosine kinase gene is progressively up regulated in the clinical course of chronic lymphocytic leukaemia conferring resistance to apoptosis. | 17 |
| 28710282 | 2017 | Function of inhibitor of Bruton's tyrosine kinase isoform α (IBTKα) in nonalcoholic steatohepatitis links autophagy and the unfolded protein response. | 13 |
| 28710282 | 2017 | Function of inhibitor of Bruton's tyrosine kinase isoform α (IBTKα) in nonalcoholic steatohepatitis links autophagy and the unfolded protein response. | 13 |
| 27827994 | 2016 | IBTK Differently Modulates Gene Expression and RNA Splicing in HeLa and K562 Cells. | 10 |
| 27827994 | 2016 | IBTK Differently Modulates Gene Expression and RNA Splicing in HeLa and K562 Cells. | 10 |
| 25882842 | 2015 | CRL3IBTK Regulates the Tumor Suppressor Pdcd4 through Ubiquitylation Coupled to Proteasomal Degradation. | 19 |
| 25882842 | 2015 | CRL3IBTK Regulates the Tumor Suppressor Pdcd4 through Ubiquitylation Coupled to Proteasomal Degradation. | 19 |
| 24648495 | 2014 | Selective mRNA translation during eIF2 phosphorylation induces expression of IBTKα. | 76 |
| 24648495 | 2014 | Selective mRNA translation during eIF2 phosphorylation induces expression of IBTKα. | 76 |
| 21482705 | 2011 | Btk regulation in human and mouse B cells via protein kinase C phosphorylation of IBtkγ. | 17 |
| 21482705 | 2011 | Btk regulation in human and mouse B cells via protein kinase C phosphorylation of IBtkγ. | 17 |
| 20721470 | 2010 | Mutations of Bruton's tyrosine kinase gene in Brazilian patients with X-linked agammaglobulinemia. | 2 |
Citation
Dessen P
IBTK (inhibitor of Bruton tyrosine kinase)
Atlas Genet Cytogenet Oncol Haematol. 2014-08-01
Online version: http://atlasgeneticsoncology.org/gene/54371/ibtk-(inhibitor-of-bruton-tyrosine-kinase)
