IQGAP3 (IQ motif containing GTPase activating protein 3)

2014-08-01  

Identity

HGNC
LOCATION
1q22
LOCUSID
ALIAS
-
FUSION GENES

Other Information

Locus ID:

NCBI: 128239
HGNC: 20669
Ensembl: ENSG00000183856

Variants:

dbSNP: 128239
ClinVar: 128239
TCGA: ENSG00000183856
COSMIC: IQGAP3

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000183856ENST00000361170Q86VI3
ENSG00000183856ENST00000491900F2Z2E2

Expression (GTEx)

0
5
10
15
20

Pathways

PathwaySourceExternal ID
Regulation of actin cytoskeletonKEGGko04810
Regulation of actin cytoskeletonKEGGhsa04810
Signal TransductionREACTOMER-HSA-162582
Signaling by Rho GTPasesREACTOMER-HSA-194315
RHO GTPase EffectorsREACTOMER-HSA-195258
RHO GTPases activate IQGAPsREACTOMER-HSA-5626467

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
382821432024Identification and validation of non-coding RNA-mediated high expression of IQGAP3 in poor prognosis of lung adenocarcinoma.1
384704972024Infiltrative Vessel Co-optive Growth Pattern Induced by IQGAP3 Overexpression Promotes Microvascular Invasion in Hepatocellular Carcinoma.0
386741302024IQGAP3 Is an Important Mediator of Skin Inflammatory Diseases.0
382821432024Identification and validation of non-coding RNA-mediated high expression of IQGAP3 in poor prognosis of lung adenocarcinoma.1
384704972024Infiltrative Vessel Co-optive Growth Pattern Induced by IQGAP3 Overexpression Promotes Microvascular Invasion in Hepatocellular Carcinoma.0
386741302024IQGAP3 Is an Important Mediator of Skin Inflammatory Diseases.0
366811152023IQGAP3 is relevant to prostate cancer: A detailed presentation of potential pathomechanisms.3
366811152023IQGAP3 is relevant to prostate cancer: A detailed presentation of potential pathomechanisms.3
354121702022CDC42 Regulates Cell Proliferation and Apoptosis in Bladder Cancer via the IQGAP3-Mediated Ras/ERK Pathway.5
361643702022Comprehensive Multiomics Analysis Identified IQGAP3 as a Potential Prognostic Marker in Pan-Cancer.2
362754582022IQGAP3 in clear cell renal cell carcinoma contributes to drug resistance and genome stability.3
354121702022CDC42 Regulates Cell Proliferation and Apoptosis in Bladder Cancer via the IQGAP3-Mediated Ras/ERK Pathway.5
361643702022Comprehensive Multiomics Analysis Identified IQGAP3 as a Potential Prognostic Marker in Pan-Cancer.2
362754582022IQGAP3 in clear cell renal cell carcinoma contributes to drug resistance and genome stability.3
341834512021IQGAP3, a YAP Target, Is Required for Proper Cell-Cycle Progression and Genome Stability.13

Citation

Dessen P

IQGAP3 (IQ motif containing GTPase activating protein 3)

Atlas Genet Cytogenet Oncol Haematol. 2014-08-01

Online version: http://atlasgeneticsoncology.org/gene/54383/iqgap3-(iq-motif-containing-gtpase-activating-protein-3)