Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 440073
MIM: 612118
HGNC: 29193
Ensembl: ENSG00000120645
Variants:
dbSNP: 440073
ClinVar: 440073
TCGA: ENSG00000120645
COSMIC: IQSEC3
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000120645 | ENST00000382841 | Q9UPP2 |
| ENSG00000120645 | ENST00000538872 | Q9UPP2 |
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Endocytosis | KEGG | ko04144 |
| Endocytosis | KEGG | hsa04144 |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 35219498 | 2022 | IQSEC3 Deletion Impairs Fear Memory Through Upregulation of Ribosomal S6K1 Signaling in the Hippocampus. | 4 |
| 35219498 | 2022 | IQSEC3 Deletion Impairs Fear Memory Through Upregulation of Ribosomal S6K1 Signaling in the Hippocampus. | 4 |
| 31680123 | 2020 | The genomic and clinical landscape of fetal akinesia. | 17 |
| 32049026 | 2020 | Loss of IQSEC3 Disrupts GABAergic Synapse Maintenance and Decreases Somatostatin Expression in the Hippocampus. | 10 |
| 31680123 | 2020 | The genomic and clinical landscape of fetal akinesia. | 17 |
| 32049026 | 2020 | Loss of IQSEC3 Disrupts GABAergic Synapse Maintenance and Decreases Somatostatin Expression in the Hippocampus. | 10 |
| 27002143 | 2016 | IQ Motif and SEC7 Domain-containing Protein 3 (IQSEC3) Interacts with Gephyrin to Promote Inhibitory Synapse Formation. | 14 |
| 27002143 | 2016 | IQ Motif and SEC7 Domain-containing Protein 3 (IQSEC3) Interacts with Gephyrin to Promote Inhibitory Synapse Formation. | 14 |
| 17981261 | 2007 | Identification of a neuron-specific human gene, KIAA1110, that is a guanine nucleotide exchange factor for ARF1. | 7 |
| 17981261 | 2007 | Identification of a neuron-specific human gene, KIAA1110, that is a guanine nucleotide exchange factor for ARF1. | 7 |
Citation
Dessen P
IQSEC3 (IQ motif and Sec7 domain ArfGEF 3)
Atlas Genet Cytogenet Oncol Haematol. 2014-08-01
Online version: http://atlasgeneticsoncology.org/gene/54384/iqsec3-(iq-motif-and-sec7-domain-arfgef-3)
