Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 79191
MIM: 612985
HGNC: 14360
Ensembl: ENSG00000177508
Variants:
dbSNP: 79191
ClinVar: 79191
TCGA: ENSG00000177508
COSMIC: IRX3
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000177508 | ENST00000329734 | P78415 |
| ENSG00000177508 | ENST00000558054 | J3QR11 |
Expression (GTEx)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 35328612 | 2022 | The Hematopoietic TALE-Code Shows Normal Activity of IRX1 in Myeloid Progenitors and Reveals Ectopic Expression of IRX3 and IRX5 in Acute Myeloid Leukemia. | 8 |
| 35957832 | 2022 | IRX3 plays an important role in the pathogenesis of metabolic-associated fatty liver disease by regulating hepatic lipid metabolism. | 4 |
| 36415696 | 2022 | Interaction analysis of FTO and IRX3 genes with obesity and related metabolic disorders in an admixed Latin American population: a possible risk increases of body weight excess. | 2 |
| 35328612 | 2022 | The Hematopoietic TALE-Code Shows Normal Activity of IRX1 in Myeloid Progenitors and Reveals Ectopic Expression of IRX3 and IRX5 in Acute Myeloid Leukemia. | 8 |
| 35957832 | 2022 | IRX3 plays an important role in the pathogenesis of metabolic-associated fatty liver disease by regulating hepatic lipid metabolism. | 4 |
| 36415696 | 2022 | Interaction analysis of FTO and IRX3 genes with obesity and related metabolic disorders in an admixed Latin American population: a possible risk increases of body weight excess. | 2 |
| 32924191 | 2021 | Clinical utility of irx3 in keratoconus. | 2 |
| 33776928 | 2021 | IRX3 Overexpression Enhances Ucp1 Expression In Vivo. | 3 |
| 34083488 | 2021 | Extensive pleiotropism and allelic heterogeneity mediate metabolic effects of IRX3 and IRX5. | 46 |
| 32924191 | 2021 | Clinical utility of irx3 in keratoconus. | 2 |
| 33776928 | 2021 | IRX3 Overexpression Enhances Ucp1 Expression In Vivo. | 3 |
| 34083488 | 2021 | Extensive pleiotropism and allelic heterogeneity mediate metabolic effects of IRX3 and IRX5. | 46 |
| 31751577 | 2020 | The homeobox factor Irx3 maintains adipogenic identity. | 7 |
| 32035736 | 2020 | Hypothalamic IRX3: A New Player in the Development of Obesity. | 15 |
| 32651404 | 2020 | Associations of nicotidamide-N-methyltransferase, FTO, and IRX3 genetic variants with body mass index and resting energy expenditure in Mexican subjects. | 7 |
Citation
Dessen P
IRX3 (iroquois homeobox 3)
Atlas Genet Cytogenet Oncol Haematol. 2014-08-01
Online version: http://atlasgeneticsoncology.org/gene/54385/irx3-(iroquois-homeobox-3)
