Identity
HGNC
LOCATION
11q13.1
LOCUSID
ALIAS
FHEIG,K2p4.1,TRAAK,TRAAK1
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 50801
MIM: 605720
HGNC: 6279
Ensembl: ENSG00000182450
Variants:
dbSNP: 50801
ClinVar: 50801
TCGA: ENSG00000182450
COSMIC: KCNK4
RNA/Proteins
Expression (GTEx)
Pathways
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37750049 | 2024 | A recurrent KCNK4 variant in a dominant pedigree with hypertrichosis and gingival fibromatosis syndrome: Variable phenotypic expressivity and insights on patients' dental management. | 0 |
| 37750049 | 2024 | A recurrent KCNK4 variant in a dominant pedigree with hypertrichosis and gingival fibromatosis syndrome: Variable phenotypic expressivity and insights on patients' dental management. | 0 |
| 32989299 | 2021 | Selective regulation of human TRAAK channels by biologically active phospholipids. | 21 |
| 33594261 | 2021 | Syndromic disorders caused by gain-of-function variants in KCNH1, KCNK4, and KCNN3-a subgroup of K(+) channelopathies. | 16 |
| 34390650 | 2021 | Physical basis for distinct basal and mechanically gated activity of the human K(+) channel TRAAK. | 10 |
| 32989299 | 2021 | Selective regulation of human TRAAK channels by biologically active phospholipids. | 21 |
| 33594261 | 2021 | Syndromic disorders caused by gain-of-function variants in KCNH1, KCNK4, and KCNN3-a subgroup of K(+) channelopathies. | 16 |
| 34390650 | 2021 | Physical basis for distinct basal and mechanically gated activity of the human K(+) channel TRAAK. | 10 |
| 31542828 | 2019 | Decreased expression of TRAAK channels in Hirschsprung's disease: a possible cause of postoperative dysmotility. | 2 |
| 31542828 | 2019 | Decreased expression of TRAAK channels in Hirschsprung's disease: a possible cause of postoperative dysmotility. | 2 |
| 30290154 | 2018 | Mutations in KCNK4 that Affect Gating Cause a Recognizable Neurodevelopmental Syndrome. | 45 |
| 30290154 | 2018 | Mutations in KCNK4 that Affect Gating Cause a Recognizable Neurodevelopmental Syndrome. | 45 |
| 26794006 | 2016 | Functional mutagenesis screens reveal the 'cap structure' formation in disulfide-bridge free TASK channels. | 7 |
| 26794006 | 2016 | Functional mutagenesis screens reveal the 'cap structure' formation in disulfide-bridge free TASK channels. | 7 |
| 25809865 | 2015 | Racial variation in breast tumor promoter methylation in the Carolina Breast Cancer Study. | 30 |
Citation
Dessen P
KCNK4 (potassium two pore domain channel subfamily K member 4)
Atlas Genet Cytogenet Oncol Haematol. 2014-08-01
Online version: http://atlasgeneticsoncology.org/gene/54394/kcnk4-(potassium-two-pore-domain-channel-subfamily-k-member-4)
