Identity
HGNC
LOCATION
16p12.1
LOCUSID
ALIAS
CGI-68,LCMT,PPMT1
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 51451
MIM: 610286
HGNC: 17557
Ensembl: ENSG00000205629
Variants:
dbSNP: 51451
ClinVar: 51451
TCGA: ENSG00000205629
COSMIC: LCMT1
RNA/Proteins
Expression (GTEx)
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37644036 | 2023 | Loss of LCMT1 and biased protein phosphatase 2A heterotrimerization drive prostate cancer progression and therapy resistance. | 5 |
| 37644036 | 2023 | Loss of LCMT1 and biased protein phosphatase 2A heterotrimerization drive prostate cancer progression and therapy resistance. | 5 |
| 27810903 | 2017 | NNMT Silencing Activates Tumor Suppressor PP2A, Inactivates Oncogenic STKs, and Inhibits Tumor Forming Ability. | 41 |
| 27810903 | 2017 | NNMT Silencing Activates Tumor Suppressor PP2A, Inactivates Oncogenic STKs, and Inhibits Tumor Forming Ability. | 41 |
| 25839665 | 2015 | A LCMT1-PME-1 methylation equilibrium controls mitotic spindle size. | 9 |
| 25839665 | 2015 | A LCMT1-PME-1 methylation equilibrium controls mitotic spindle size. | 9 |
| 22443683 | 2013 | The biogenesis of active protein phosphatase 2A holoenzymes: a tightly regulated process creating phosphatase specificity. | 101 |
| 23943618 | 2013 | Leucine carboxyl methyltransferase 1 (LCMT1)-dependent methylation regulates the association of protein phosphatase 2A and Tau protein with plasma membrane microdomains in neuroblastoma cells. | 19 |
| 22443683 | 2013 | The biogenesis of active protein phosphatase 2A holoenzymes: a tightly regulated process creating phosphatase specificity. | 101 |
| 23943618 | 2013 | Leucine carboxyl methyltransferase 1 (LCMT1)-dependent methylation regulates the association of protein phosphatase 2A and Tau protein with plasma membrane microdomains in neuroblastoma cells. | 19 |
| 22732552 | 2012 | Glycogen synthase kinase-3β regulates leucine-309 demethylation of protein phosphatase-2A via PPMT1 and PME-1. | 14 |
| 22732552 | 2012 | Glycogen synthase kinase-3β regulates leucine-309 demethylation of protein phosphatase-2A via PPMT1 and PME-1. | 14 |
| 21206058 | 2011 | The structure of human leucine carboxyl methyltransferase 1 that regulates protein phosphatase PP2A. | 4 |
| 21292165 | 2011 | The structural basis for tight control of PP2A methylation and function by LCMT-1. | 72 |
| 21206058 | 2011 | The structure of human leucine carboxyl methyltransferase 1 that regulates protein phosphatase PP2A. | 4 |
Citation
Dessen P
LCMT1 (leucine carboxyl methyltransferase 1)
Atlas Genet Cytogenet Oncol Haematol. 2014-08-01
Online version: http://atlasgeneticsoncology.org/gene/54420/lcmt1-(leucine-carboxyl-methyltransferase-1)
