Identity
HGNC
LOCATION
6p21.31
LOCUSID
ALIAS
CTRCT42,LEM2,MARUPS,NET25,dJ482C21.1
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 221496
MIM: 616312
HGNC: 21244
Ensembl: ENSG00000161904
Variants:
dbSNP: 221496
ClinVar: 221496
TCGA: ENSG00000161904
COSMIC: LEMD2
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 36656966 | 2023 | The Role of the LEMD2 p.L13R Mutation in Dilated Cardiomyopathy. | 0 |
| 36656966 | 2023 | The Role of the LEMD2 p.L13R Mutation in Dilated Cardiomyopathy. | 0 |
| 36377660 | 2022 | Loss of function of the nuclear envelope protein LEMD2 causes DNA damage-dependent cardiomyopathy. | 5 |
| 36377660 | 2022 | Loss of function of the nuclear envelope protein LEMD2 causes DNA damage-dependent cardiomyopathy. | 5 |
| 33319920 | 2021 | SATB2-LEMD2 interaction links nuclear shape plasticity to regulation of cognition-related genes. | 12 |
| 33319920 | 2021 | SATB2-LEMD2 interaction links nuclear shape plasticity to regulation of cognition-related genes. | 12 |
| 32085595 | 2020 | Comparative Interactome Analysis of Emerin, MAN1 and LEM2 Reveals a Unique Role for LEM2 in Nucleotide Excision Repair. | 12 |
| 32271860 | 2020 | Regulated lipid synthesis and LEM2/CHMP7 jointly control nuclear envelope closure. | 35 |
| 32494070 | 2020 | LEM2 phase separation promotes ESCRT-mediated nuclear envelope reformation. | 71 |
| 32085595 | 2020 | Comparative Interactome Analysis of Emerin, MAN1 and LEM2 Reveals a Unique Role for LEM2 in Nucleotide Excision Repair. | 12 |
| 32271860 | 2020 | Regulated lipid synthesis and LEM2/CHMP7 jointly control nuclear envelope closure. | 35 |
| 32494070 | 2020 | LEM2 phase separation promotes ESCRT-mediated nuclear envelope reformation. | 71 |
| 30905398 | 2019 | The Discovery of a LEMD2-Associated Nuclear Envelopathy with Early Progeroid Appearance Suggests Advanced Applications for AI-Driven Facial Phenotyping. | 21 |
| 31147383 | 2019 | Repair of nuclear ruptures requires barrier-to-autointegration factor. | 75 |
| 30905398 | 2019 | The Discovery of a LEMD2-Associated Nuclear Envelopathy with Early Progeroid Appearance Suggests Advanced Applications for AI-Driven Facial Phenotyping. | 21 |
Citation
Dessen P
LEMD2 (LEM domain nuclear envelope protein 2)
Atlas Genet Cytogenet Oncol Haematol. 2014-08-01
Online version: http://atlasgeneticsoncology.org/gene/54422/lemd2-(lem-domain-nuclear-envelope-protein-2)
