Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 23175
MIM: 605518
HGNC: 13345
Ensembl: ENSG00000134324
Variants:
dbSNP: 23175
ClinVar: 23175
TCGA: ENSG00000134324
COSMIC: LPIN1
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
PharmGKB
| Entity ID | Name | Type | Evidence | Association | PK | PD | PMIDs |
|---|---|---|---|---|---|---|---|
| PA443890 | Diabetes Mellitus, Type 2 | Disease | ClinicalAnnotation | associated | PD | 18693052 | |
| PA451283 | rosiglitazone | Chemical | ClinicalAnnotation | associated | PD | 18693052 |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37776435 | 2024 | Haploinsufficiency of Lipin3 leads to hypertriglyceridemia and obesity by disrupting the expression and nucleocytoplasmic localization of Lipin1. | 2 |
| 37776435 | 2024 | Haploinsufficiency of Lipin3 leads to hypertriglyceridemia and obesity by disrupting the expression and nucleocytoplasmic localization of Lipin1. | 2 |
| 37150031 | 2023 | Hydroxychloroquine sulfate: A novel treatment for lipin-1 deficiency? | 1 |
| 37150031 | 2023 | Hydroxychloroquine sulfate: A novel treatment for lipin-1 deficiency? | 1 |
| 35222395 | 2022 | LPIN1 Is a Regulatory Factor Associated With Immune Response and Inflammation in Sepsis. | 11 |
| 35222395 | 2022 | LPIN1 Is a Regulatory Factor Associated With Immune Response and Inflammation in Sepsis. | 11 |
| 33274548 | 2021 | LPIN1 downregulation enhances anticancer activity of the novel HDAC/PI3K dual inhibitor FK-A11. | 2 |
| 33300687 | 2021 | Use of dexamethasone in idiopathic, acute pediatric rhabdomyolysis. | 2 |
| 33456573 | 2021 | Lipin 1 deficiency causes adult-onset myasthenia with motor neuron dysfunction in humans and neuromuscular junction defects in zebrafish. | 9 |
| 33596934 | 2021 | Identification of lipidomic profiles associated with drug-resistant prostate cancer cells. | 11 |
| 34197731 | 2021 | Whole-exome sequencing reveals common and rare variants in immunologic and neurological genes implicated in achalasia. | 6 |
| 34467247 | 2021 | Compromised mitochondrial quality control triggers lipin1-related rhabdomyolysis. | 6 |
| 34576941 | 2021 | NLIP and HAD-like Domains of Pah1 and Lipin 1 Phosphatidate Phosphatases Are Essential for Their Catalytic Activities. | 5 |
| 33274548 | 2021 | LPIN1 downregulation enhances anticancer activity of the novel HDAC/PI3K dual inhibitor FK-A11. | 2 |
| 33300687 | 2021 | Use of dexamethasone in idiopathic, acute pediatric rhabdomyolysis. | 2 |
Citation
Dessen P
LPIN1 (lipin 1)
Atlas Genet Cytogenet Oncol Haematol. 2014-08-01
Online version: http://atlasgeneticsoncology.org/gene/54427/
