Identity
HGNC
LOCATION
6p12.1
LOCUSID
ALIAS
LANO,dJ523E19.1
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 55227
MIM: 608195
HGNC: 14307
Ensembl: ENSG00000137269
Variants:
dbSNP: 55227
ClinVar: 55227
TCGA: ENSG00000137269
COSMIC: LRRC1
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000137269 | ENST00000370882 | Q5T0G3 |
| ENSG00000137269 | ENST00000370888 | Q9BTT6 |
| ENSG00000137269 | ENST00000487251 | Q9BTT6 |
Expression (GTEx)
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38165568 | 2024 | LRRC1 knockdown downregulates MACF1 to inhibit the malignant progression of acute myeloid leukemia by inactivating β-catenin/c-Myc signaling. | 1 |
| 38473980 | 2024 | The Upregulation of Leucine-Rich Repeat Containing 1 Expression Activates Hepatic Stellate Cells and Promotes Liver Fibrosis by Stabilizing Phosphorylated Smad2/3. | 0 |
| 38165568 | 2024 | LRRC1 knockdown downregulates MACF1 to inhibit the malignant progression of acute myeloid leukemia by inactivating β-catenin/c-Myc signaling. | 1 |
| 38473980 | 2024 | The Upregulation of Leucine-Rich Repeat Containing 1 Expression Activates Hepatic Stellate Cells and Promotes Liver Fibrosis by Stabilizing Phosphorylated Smad2/3. | 0 |
| 36370237 | 2023 | The downstream PPARγ target LRRC1 participates in early stage adipocytic differentiation. | 3 |
| 36370237 | 2023 | The downstream PPARγ target LRRC1 participates in early stage adipocytic differentiation. | 3 |
| 32978367 | 2020 | Bone marrow mesenchymal stem cells-derived exosomal microRNA-193a reduces cisplatin resistance of non-small cell lung cancer cells via targeting LRRC1. | 62 |
| 32978367 | 2020 | Bone marrow mesenchymal stem cells-derived exosomal microRNA-193a reduces cisplatin resistance of non-small cell lung cancer cells via targeting LRRC1. | 62 |
| 31513346 | 2019 | The Tumor Suppressor SCRIB is a Negative Modulator of the Wnt/β-Catenin Signaling Pathway. | 10 |
| 31513346 | 2019 | The Tumor Suppressor SCRIB is a Negative Modulator of the Wnt/β-Catenin Signaling Pathway. | 10 |
| 30344009 | 2018 | The SCRIB Paralog LANO/LRRC1 Regulates Breast Cancer Stem Cell Fate through WNT/β-Catenin Signaling. | 10 |
| 30344009 | 2018 | The SCRIB Paralog LANO/LRRC1 Regulates Breast Cancer Stem Cell Fate through WNT/β-Catenin Signaling. | 10 |
| 23645086 | 2013 | Aberrant upregulation of LRRC1 contributes to human hepatocellular carcinoma. | 15 |
| 23645086 | 2013 | Aberrant upregulation of LRRC1 contributes to human hepatocellular carcinoma. | 15 |
Citation
Dessen P
LRRC1 (leucine rich repeat containing 1)
Atlas Genet Cytogenet Oncol Haematol. 2014-08-01
Online version: http://atlasgeneticsoncology.org/gene/54430/lrrc1-(leucine-rich-repeat-containing-1)
