Identity
HGNC
LOCATION
17q21.33
LOCUSID
ALIAS
PRO1855,p34
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 55379
MIM: 614854
HGNC: 28817
Ensembl: ENSG00000108829
Variants:
dbSNP: 55379
ClinVar: 55379
TCGA: ENSG00000108829
COSMIC: LRRC59
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000108829 | ENST00000225972 | Q96AG4 |
| ENSG00000108829 | ENST00000503118 | I3L2E8 |
| ENSG00000108829 | ENST00000576448 | I3L223 |
Expression (GTEx)
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37706625 | 2023 | LRRC59 serves as a novel biomarker for predicting the progression and prognosis of bladder cancer. | 3 |
| 37706625 | 2023 | LRRC59 serves as a novel biomarker for predicting the progression and prognosis of bladder cancer. | 3 |
| 31068071 | 2020 | LRRC59 modulates type I interferon signaling by restraining the SQSTM1/p62-mediated autophagic degradation of pattern recognition receptor DDX58/RIG-I. | 36 |
| 32788342 | 2020 | Quantitative Proteomics Links the LRRC59 Interactome to mRNA Translation on the ER Membrane. | 14 |
| 31068071 | 2020 | LRRC59 modulates type I interferon signaling by restraining the SQSTM1/p62-mediated autophagic degradation of pattern recognition receptor DDX58/RIG-I. | 36 |
| 32788342 | 2020 | Quantitative Proteomics Links the LRRC59 Interactome to mRNA Translation on the ER Membrane. | 14 |
| 30650545 | 2019 | Targeting of LRRC59 to the Endoplasmic Reticulum and the Inner Nuclear Membrane. | 12 |
| 30650545 | 2019 | Targeting of LRRC59 to the Endoplasmic Reticulum and the Inner Nuclear Membrane. | 12 |
| 25833693 | 2015 | Leucine-rich repeat-containing protein 59 mediates nuclear import of cancerous inhibitor of PP2A in prostate cancer cells. | 11 |
| 26466955 | 2015 | LRRC59 Regulates Trafficking of Nucleic Acid-Sensing TLRs from the Endoplasmic Reticulum via Association with UNC93B1. | 20 |
| 25833693 | 2015 | Leucine-rich repeat-containing protein 59 mediates nuclear import of cancerous inhibitor of PP2A in prostate cancer cells. | 11 |
| 26466955 | 2015 | LRRC59 Regulates Trafficking of Nucleic Acid-Sensing TLRs from the Endoplasmic Reticulum via Association with UNC93B1. | 20 |
| 22321063 | 2012 | Nuclear import of exogenous FGF1 requires the ER-protein LRRC59 and the importins Kpnα1 and Kpnβ1. | 35 |
| 22321063 | 2012 | Nuclear import of exogenous FGF1 requires the ER-protein LRRC59 and the importins Kpnα1 and Kpnβ1. | 35 |
Citation
Dessen P
LRRC59 (leucine rich repeat containing 59)
Atlas Genet Cytogenet Oncol Haematol. 2014-08-01
Online version: http://atlasgeneticsoncology.org/gene/54434/lrrc59-(leucine-rich-repeat-containing-59)
