Identity
HGNC
LOCATION
6q22.31
LOCUSID
ALIAS
HUMM3,HUMM9,MAN9
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 4121
MIM: 604344
HGNC: 6821
Ensembl: ENSG00000111885
Variants:
dbSNP: 4121
ClinVar: 4121
TCGA: ENSG00000111885
COSMIC: MAN1A1
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000111885 | ENST00000368468 | P33908 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 33196586 | 2021 | Identification of a Novel MAN1A1-ROS1 Fusion Gene Through mRNA-based Screening for Tyrosine Kinase Gene Aberrations in a Patient with Leiomyosarcoma. | 7 |
| 33196586 | 2021 | Identification of a Novel MAN1A1-ROS1 Fusion Gene Through mRNA-based Screening for Tyrosine Kinase Gene Aberrations in a Patient with Leiomyosarcoma. | 7 |
| 32331836 | 2020 | Markers of malignant prostate cancer cells: Golgi localization of α-mannosidase 1A at GM130-GRASP65 site and appearance of high mannose N-glycans on cell surface. | 11 |
| 32331836 | 2020 | Markers of malignant prostate cancer cells: Golgi localization of α-mannosidase 1A at GM130-GRASP65 site and appearance of high mannose N-glycans on cell surface. | 11 |
| 31659304 | 2019 | Prognostic relevance of the Golgi mannosidase MAN1A1 in ovarian cancer: impact of N-glycosylation on tumour cell aggregation. | 17 |
| 31659304 | 2019 | Prognostic relevance of the Golgi mannosidase MAN1A1 in ovarian cancer: impact of N-glycosylation on tumour cell aggregation. | 17 |
| 28782625 | 2017 | Shifted Golgi targeting of glycosyltransferases and α-mannosidase IA from giantin to GM130-GRASP65 results in formation of high mannose N-glycans in aggressive prostate cancer cells. | 11 |
| 28782625 | 2017 | Shifted Golgi targeting of glycosyltransferases and α-mannosidase IA from giantin to GM130-GRASP65 results in formation of high mannose N-glycans in aggressive prostate cancer cells. | 11 |
| 23911047 | 2013 | Lysosomal exoglycosidases in nasal polyps. | 0 |
| 23911047 | 2013 | Lysosomal exoglycosidases in nasal polyps. | 0 |
| 21577142 | 2011 | Differential expression and function of α-mannosidase I in stimulated naive and memory CD4+ T cells. | 6 |
| 21577142 | 2011 | Differential expression and function of α-mannosidase I in stimulated naive and memory CD4+ T cells. | 6 |
| 20379614 | 2010 | Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. | 78 |
| 20379614 | 2010 | Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. | 78 |
| 19258393 | 2009 | The mammalian UPR boosts glycoprotein ERAD by suppressing the proteolytic downregulation of ER mannosidase I. | 28 |
Citation
Dessen P
MAN1A1 (mannosidase alpha class 1A member 1)
Atlas Genet Cytogenet Oncol Haematol. 2014-08-01
Online version: http://atlasgeneticsoncology.org/gene/54440/man1a1-(mannosidase-alpha-class-1a-member-1)
