MAN1A2 (mannosidase alpha class 1A member 2)

2014-08-01  

Identity

HGNC
LOCATION
1p12
LOCUSID
ALIAS
MAN1B
FUSION GENES

Other Information

Locus ID:

NCBI: 10905
MIM: 604345
HGNC: 6822
Ensembl: ENSG00000198162

Variants:

dbSNP: 10905
ClinVar: 10905
TCGA: ENSG00000198162
COSMIC: MAN1A2

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000198162ENST00000356554O60476
ENSG00000198162ENST00000421535H0Y543
ENSG00000198162ENST00000422329Q5T9E3
ENSG00000198162ENST00000449370H0Y7H1

Expression (GTEx)

0
5
10
15
20
25

Pathways

PathwaySourceExternal ID
N-Glycan biosynthesisKEGGko00510
N-Glycan biosynthesisKEGGhsa00510
Metabolic pathwaysKEGGhsa01100
Protein processing in endoplasmic reticulumKEGGko04141
Protein processing in endoplasmic reticulumKEGGhsa04141
N-glycan precursor trimmingKEGGhsa_M00073
N-glycan precursor trimmingKEGGM00073
Metabolism of proteinsREACTOMER-HSA-392499
Post-translational protein modificationREACTOMER-HSA-597592
Asparagine N-linked glycosylationREACTOMER-HSA-446203
Transport to the Golgi and subsequent modificationREACTOMER-HSA-948021
N-glycan trimming and elongation in the cis-GolgiREACTOMER-HSA-964739
Progressive trimming of alpha-1,2-linked mannose residues from Man9/8/7GlcNAc2 to produce Man5GlcNAc2REACTOMER-HSA-964827
Vesicle-mediated transportREACTOMER-HSA-5653656
Membrane TraffickingREACTOMER-HSA-199991
Intra-Golgi and retrograde Golgi-to-ER trafficREACTOMER-HSA-6811442
Intra-Golgi trafficREACTOMER-HSA-6811438

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.62
189876182009Screening for replication of genome-wide SNP associations in sporadic ALS.14

Citation

Dessen P

MAN1A2 (mannosidase alpha class 1A member 2)

Atlas Genet Cytogenet Oncol Haematol. 2014-08-01

Online version: http://atlasgeneticsoncology.org/gene/54441/man1a2-(mannosidase-alpha-class-1a-member-2)