MCMBP (minichromosome maintenance complex binding protein)

2014-08-01  

Identity

HGNC
LOCATION
10q26.11
LOCUSID
ALIAS
C10orf119,MCM-BP
FUSION GENES

Other Information

Locus ID:

NCBI: 79892
MIM: 610909
HGNC: 25782
Ensembl: ENSG00000197771

Variants:

dbSNP: 79892
ClinVar: 79892
TCGA: ENSG00000197771
COSMIC: MCMBP

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000197771ENST00000360003Q9BTE3
ENSG00000197771ENST00000369077Q9BTE3
ENSG00000197771ENST00000369077A0A0S2Z5P5

Expression (GTEx)

0
5
10
15
20
25
30
35
40
45

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
354386322022MCMBP promotes the assembly of the MCM2-7 hetero-hexamer to ensure robust DNA replication in human cells.13
354386322022MCMBP promotes the assembly of the MCM2-7 hetero-hexamer to ensure robust DNA replication in human cells.13
241909672014A role for USP7 in DNA replication.38
252462712014Deregulation of the replisome factor MCMBP prompts oncogenesis in colorectal carcinomas through chromosomal instability.11
241909672014A role for USP7 in DNA replication.38
252462712014Deregulation of the replisome factor MCMBP prompts oncogenesis in colorectal carcinomas through chromosomal instability.11
222502012012The MCM-associated protein MCM-BP is important for human nuclear morphology.16
225400122012Interactions of the human MCM-BP protein with MCM complex components and Dbf4.10
222502012012The MCM-associated protein MCM-BP is important for human nuclear morphology.16
225400122012Interactions of the human MCM-BP protein with MCM complex components and Dbf4.10
211964932011MCM-BP regulates unloading of the MCM2-7 helicase in late S phase.34
211964932011MCM-BP regulates unloading of the MCM2-7 helicase in late S phase.34
200909392010The MCM-binding protein ETG1 aids sister chromatid cohesion required for postreplicative homologous recombination repair.35
200909392010The MCM-binding protein ETG1 aids sister chromatid cohesion required for postreplicative homologous recombination repair.35
172967312007Identification and characterization of a novel component of the human minichromosome maintenance complex.33

Citation

Dessen P

MCMBP (minichromosome maintenance complex binding protein)

Atlas Genet Cytogenet Oncol Haematol. 2014-08-01

Online version: http://atlasgeneticsoncology.org/gene/54446/mcmbp-(minichromosome-maintenance-complex-binding-protein)