MICALL1 (MICAL like 1)

2014-08-01  

Identity

HGNC
MICALL1
LOCATION
22q13.1
LOCUSID
85377
ALIAS
MICAL-L1,MIRAB13
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 85377
HGNC: 29804
Ensembl: ENSG00000100139

Variants:

dbSNP: 85377
ClinVar: 85377
TCGA: ENSG00000100139
COSMIC: MICALL1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000100139ENST00000215957Q8N3F8
ENSG00000100139ENST00000424008B0QY91
ENSG00000100139ENST00000445494B0QY86
ENSG00000100139ENST00000454685H0Y6J8

Expression (GTEx)

0
10
20
30
40
50
60
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
198644582009MICAL-L1 links EHD1 to tubular recycling endosomes and regulates receptor recycling.82
235963232013Cooperation of MICAL-L1, syndapin2, and phosphatidic acid in tubular recycling endosome biogenesis.46
219517252012MICAL-L1 is a tubular endosomal membrane hub that connects Rab35 and Arf6 with Rab8a.44
252487442014Diacylglycerol kinase α regulates tubular recycling endosome biogenesis and major histocompatibility complex class I recycling.15
217953892011MICAL-like1 mediates epidermal growth factor receptor endocytosis.13
252871872015Novel functions for the endocytic regulatory proteins MICAL-L1 and EHD1 in mitosis.12
244818182014Regulation of Src trafficking and activation by the endocytic regulatory proteins MICAL-L1 and EHD1.10
287145182017Regulation of tubular recycling endosome biogenesis by the p53-MICALL1 pathway.2

Citation

Dessen P

MICALL1 (MICAL like 1)

Atlas Genet Cytogenet Oncol Haematol. 2014-08-01

Online version: http://atlasgeneticsoncology.org/gene/54456/micall1-(mical-like-1)