Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 23417
MIM: 606761
HGNC: 7150
Ensembl: ENSG00000103150
Variants:
dbSNP: 23417
ClinVar: 23417
TCGA: ENSG00000103150
COSMIC: MLYCD
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000103150 | ENST00000262430 | O95822 |
| ENSG00000103150 | ENST00000561562 | A0A087X1B8 |
| ENSG00000103150 | ENST00000563312 | V9GYW3 |
| ENSG00000103150 | ENST00000566309 | V9GY18 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
PharmGKB
| Entity ID | Name | Type | Evidence | Association | PK | PD | PMIDs |
|---|---|---|---|---|---|---|---|
| PA33744 | PRKAA1 | Gene | Pathway | associated | 22722338 | ||
| PA33745 | PRKAA2 | Gene | Pathway | associated | 22722338 | ||
| PA33746 | PRKAB1 | Gene | Pathway | associated | 22722338 | ||
| PA33747 | PRKAB2 | Gene | Pathway | associated | 22722338 | ||
| PA33751 | PRKAG1 | Gene | Pathway | associated | 22722338 | ||
| PA33752 | PRKAG2 | Gene | Pathway | associated | 22722338 | ||
| PA33753 | PRKAG3 | Gene | Pathway | associated | 22722338 |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 26858006 | 2016 | A new case of malonyl-CoA decarboxylase deficiency with mild clinical features. | 4 |
| 26948533 | 2016 | Identification of the active site of human mitochondrial malonyl-coenzyme a decarboxylase: A combined computational study. | 1 |
| 26858006 | 2016 | A new case of malonyl-CoA decarboxylase deficiency with mild clinical features. | 4 |
| 26948533 | 2016 | Identification of the active site of human mitochondrial malonyl-coenzyme a decarboxylase: A combined computational study. | 1 |
| 23482565 | 2013 | Structural asymmetry and disulfide bridges among subunits modulate the activity of human malonyl-CoA decarboxylase. | 5 |
| 23791943 | 2013 | Crystal structures of malonyl-coenzyme A decarboxylase provide insights into its catalytic mechanism and disease-causing mutations. | 8 |
| 23482565 | 2013 | Structural asymmetry and disulfide bridges among subunits modulate the activity of human malonyl-CoA decarboxylase. | 5 |
| 23791943 | 2013 | Crystal structures of malonyl-coenzyme A decarboxylase provide insights into its catalytic mechanism and disease-causing mutations. | 8 |
| 22778304 | 2012 | Malonyl coenzyme A decarboxylase deficiency: early dietary restriction and time course of cardiomyopathy. | 10 |
| 22778304 | 2012 | Malonyl coenzyme A decarboxylase deficiency: early dietary restriction and time course of cardiomyopathy. | 10 |
| 20702857 | 2010 | Fatty acid oxidation and malonyl-CoA decarboxylase in the vascular remodeling of pulmonary hypertension. | 109 |
| 20877624 | 2010 | Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression. | 20 |
| 20702857 | 2010 | Fatty acid oxidation and malonyl-CoA decarboxylase in the vascular remodeling of pulmonary hypertension. | 109 |
| 20877624 | 2010 | Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression. | 20 |
| 18314420 | 2008 | Malonyl CoenzymeA decarboxylase regulates lipid and glucose metabolism in human skeletal muscle. | 32 |
Citation
Dessen P
MLYCD (malonyl-CoA decarboxylase)
Atlas Genet Cytogenet Oncol Haematol. 2014-08-01
Online version: http://atlasgeneticsoncology.org/gene/54463/mlycd-(malonyl-coa-decarboxylase)
