MOBP (myelin associated oligodendrocyte basic protein)

2014-08-01  

Identity

HGNC
MOBP
LOCATION
3p22.1
LOCUSID
4336
ALIAS
-
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 4336
MIM: 600948
HGNC: 7189
Ensembl: ENSG00000168314

Variants:

dbSNP: 4336
ClinVar: 4336
TCGA: ENSG00000168314
COSMIC: MOBP

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000168314ENST00000311042Q13875
ENSG00000168314ENST00000383754Q13875
ENSG00000168314ENST00000383754A0A0S2Z3W1
ENSG00000168314ENST00000415443Q13875
ENSG00000168314ENST00000415443A0A0S2Z3W1
ENSG00000168314ENST00000420739Q13875
ENSG00000168314ENST00000420739A0A024R2N4
ENSG00000168314ENST00000424090Q13875
ENSG00000168314ENST00000424090A0A024R2N4
ENSG00000168314ENST00000428261Q13875
ENSG00000168314ENST00000428261A0A0S2Z3W1
ENSG00000168314ENST00000436143C9JLT8
ENSG00000168314ENST00000441980Q13875
ENSG00000168314ENST00000441980A0A024R2N4
ENSG00000168314ENST00000442631Q13875
ENSG00000168314ENST00000442631A0A024R2P3
ENSG00000168314ENST00000447324Q13875
ENSG00000168314ENST00000447324A0A0S2Z3W1
ENSG00000168314ENST00000451925C9JAR7
ENSG00000168314ENST00000452959Q13875
ENSG00000168314ENST00000452959A0A0S2Z3W1

Expression (GTEx)

0
500
1000
1500
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

PharmGKB

Entity IDNameTypeEvidenceAssociationPKPDPMIDs
PA164778930creatineChemicalClinicalAnnotationassociatedPD31624333
PA443332Amyotrophic Lateral SclerosisDiseaseClinicalAnnotationassociatedPD31624333

References

Pubmed IDYearTitleCitations
346946302022Myelin-associated oligodendrocyte basic protein rs616147 polymorphism as a risk factor for Parkinson's disease.11
346946302022Myelin-associated oligodendrocyte basic protein rs616147 polymorphism as a risk factor for Parkinson's disease.11
333685492021MOBP and HIP1 in multiple system atrophy: New α-synuclein partners in glial cytoplasmic inclusions implicated in the disease pathogenesis.10
349462822021MOBP rs616147 Polymorphism and Risk of Amyotrophic Lateral Sclerosis in a Greek Population: A Case-Control Study.2
333685492021MOBP and HIP1 in multiple system atrophy: New α-synuclein partners in glial cytoplasmic inclusions implicated in the disease pathogenesis.10
349462822021MOBP rs616147 Polymorphism and Risk of Amyotrophic Lateral Sclerosis in a Greek Population: A Case-Control Study.2
311550122020Dentate gyrus volume deficit in schizophrenia.16
315352032020White matter DNA methylation profiling reveals deregulation of HIP1, LMAN2, MOBP, and other loci in multiple system atrophy.25
311550122020Dentate gyrus volume deficit in schizophrenia.16
315352032020White matter DNA methylation profiling reveals deregulation of HIP1, LMAN2, MOBP, and other loci in multiple system atrophy.25
311839262019Immunoreactivity of myelin-associated oligodendrocytic basic protein in Lewy bodies.7
311839262019Immunoreactivity of myelin-associated oligodendrocytic basic protein in Lewy bodies.7
274553482016Genome-wide association analyses identify new risk variants and the genetic architecture of amyotrophic lateral sclerosis.274
274553482016Genome-wide association analyses identify new risk variants and the genetic architecture of amyotrophic lateral sclerosis.274
260779512015Genome-wide association study of corticobasal degeneration identifies risk variants shared with progressive supranuclear palsy.105

Citation

Dessen P

MOBP (myelin associated oligodendrocyte basic protein)

Atlas Genet Cytogenet Oncol Haematol. 2014-08-01

Online version: http://atlasgeneticsoncology.org/gene/54464/mobp-(myelin-associated-oligodendrocyte-basic-protein)