Identity
HGNC
LOCATION
3q13.31
LOCUSID
ALIAS
MAK3,NAT13,NAT13P,NAT5,NAT5P,SAN,hNaa50p
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 80218
MIM: 610834
HGNC: 29533
Ensembl: ENSG00000121579
Variants:
dbSNP: 80218
ClinVar: 80218
TCGA: ENSG00000121579
COSMIC: NAA50
RNA/Proteins
Expression (GTEx)
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 27422821 | 2016 | Opposing Functions of the N-terminal Acetyltransferases Naa50 and NatA in Sister-chromatid Cohesion. | 7 |
| 27484799 | 2016 | Human Naa50 Protein Displays Broad Substrate Specificity for Amino-terminal Acetylation: DETAILED STRUCTURAL AND BIOCHEMICAL ANALYSIS USING TETRAPEPTIDE LIBRARY. | 7 |
| 27422821 | 2016 | Opposing Functions of the N-terminal Acetyltransferases Naa50 and NatA in Sister-chromatid Cohesion. | 7 |
| 27484799 | 2016 | Human Naa50 Protein Displays Broad Substrate Specificity for Amino-terminal Acetylation: DETAILED STRUCTURAL AND BIOCHEMICAL ANALYSIS USING TETRAPEPTIDE LIBRARY. | 7 |
| 25886145 | 2015 | N-terminal acetylome analysis reveals the specificity of Naa50 (Nat5) and suggests a kinetic competition between N-terminal acetyltransferases and methionine aminopeptidases. | 29 |
| 25886145 | 2015 | N-terminal acetylome analysis reveals the specificity of Naa50 (Nat5) and suggests a kinetic competition between N-terminal acetyltransferases and methionine aminopeptidases. | 29 |
| 23557624 | 2013 | Design, synthesis, and kinetic characterization of protein N-terminal acetyltransferase inhibitors. | 30 |
| 23557624 | 2013 | Design, synthesis, and kinetic characterization of protein N-terminal acetyltransferase inhibitors. | 30 |
| 22311970 | 2012 | Human protein N-terminal acetyltransferase hNaa50p (hNAT5/hSAN) follows ordered sequential catalytic mechanism: combined kinetic and NMR study. | 14 |
| 22311970 | 2012 | Human protein N-terminal acetyltransferase hNaa50p (hNAT5/hSAN) follows ordered sequential catalytic mechanism: combined kinetic and NMR study. | 14 |
| 21900231 | 2011 | Structure of a ternary Naa50p (NAT5/SAN) N-terminal acetyltransferase complex reveals the molecular basis for substrate-specific acetylation. | 58 |
| 21900231 | 2011 | Structure of a ternary Naa50p (NAT5/SAN) N-terminal acetyltransferase complex reveals the molecular basis for substrate-specific acetylation. | 58 |
| 19398576 | 2009 | Knockdown of human N alpha-terminal acetyltransferase complex C leads to p53-dependent apoptosis and aberrant human Arl8b localization. | 64 |
| 19744929 | 2009 | Human Naa50p (Nat5/San) displays both protein N alpha- and N epsilon-acetyltransferase activity. | 57 |
| 19398576 | 2009 | Knockdown of human N alpha-terminal acetyltransferase complex C leads to p53-dependent apoptosis and aberrant human Arl8b localization. | 64 |
Citation
Dessen P
NAA50 (N-alpha-acetyltransferase 50, NatE catalytic subunit)
Atlas Genet Cytogenet Oncol Haematol. 2014-08-01
Online version: http://atlasgeneticsoncology.org/gene/54485/gene-fusions-explorer/new-content/
