NAV1 (neuron navigator 1)

2014-08-01  

Identity

HGNC
NAV1
LOCATION
1q32.1
LOCUSID
89796
ALIAS
POMFIL3,STEERIN1,UNC53H1
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 89796
MIM: 611628
HGNC: 15989
Ensembl: ENSG00000134369

Variants:

dbSNP: 89796
ClinVar: 89796
TCGA: ENSG00000134369
COSMIC: NAV1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000134369ENST00000367295Q8NEY1
ENSG00000134369ENST00000367296Q8NEY1
ENSG00000134369ENST00000367302A0A0A0MRJ3
ENSG00000134369ENST00000430015H0Y6F6
ENSG00000134369ENST00000438083H7BZD9
ENSG00000134369ENST00000477118H0YA94

Expression (GTEx)

0
5
10
15
20
25
30
35
40
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
381726362024Na(v)1.7 as a chondrocyte regulator and therapeutic target for osteoarthritis.4
383390222024Functional Characteristics of the Nav1.1 p.Arg1596Cys Mutation Associated with Varying Severity of Epilepsy Phenotypes.1
381726362024Na(v)1.7 as a chondrocyte regulator and therapeutic target for osteoarthritis.4
383390222024Functional Characteristics of the Nav1.1 p.Arg1596Cys Mutation Associated with Varying Severity of Epilepsy Phenotypes.1
321417892019Genetic Association Analyses Highlight IL6, ALPL, and NAV1 As 3 New Susceptibility Genes Underlying Calcific Aortic Valve Stenosis.30
321417892019Genetic Association Analyses Highlight IL6, ALPL, and NAV1 As 3 New Susceptibility Genes Underlying Calcific Aortic Valve Stenosis.30
250657582014Dynamic microtubules catalyze formation of navigator-TRIO complexes to regulate neurite extension.41
250657582014Dynamic microtubules catalyze formation of navigator-TRIO complexes to regulate neurite extension.41
250657582014Dynamic microtubules catalyze formation of navigator-TRIO complexes to regulate neurite extension.41
250657582014Dynamic microtubules catalyze formation of navigator-TRIO complexes to regulate neurite extension.41
120792792002Neuron navigator: a human gene family with homology to unc-53, a cell guidance gene from Caenorhabditis elegans.51
120792792002Neuron navigator: a human gene family with homology to unc-53, a cell guidance gene from Caenorhabditis elegans.51

Citation

Dessen P

NAV1 (neuron navigator 1)

Atlas Genet Cytogenet Oncol Haematol. 2014-08-01

Online version: http://atlasgeneticsoncology.org/gene/54489/nav1-(neuron-navigator-1)