Identity
HGNC
LOCATION
12p13.31
LOCUSID
ALIAS
CAP-D2,CNAP1,MCPH21,hCAP-D2
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 9918
MIM: 615638
HGNC: 24305
Ensembl: ENSG00000010292
Variants:
dbSNP: 9918
ClinVar: 9918
TCGA: ENSG00000010292
COSMIC: NCAPD2
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000010292 | ENST00000315579 | Q15021 |
| ENSG00000010292 | ENST00000382457 | E7EN77 |
| ENSG00000010292 | ENST00000539084 | F5H431 |
| ENSG00000010292 | ENST00000539714 | F5GZK7 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 35348268 | 2023 | NCAPD2 promotes breast cancer progression through E2F1 transcriptional regulation of CDK1. | 8 |
| 36701707 | 2023 | NCAPD2 is a novel marker for the poor prognosis of lung adenocarcinoma and is associated with immune infiltration and tumor mutational burden. | 3 |
| 37498296 | 2023 | Non-SMC condensin I complex subunit D2 (NCAPD2) reveals its prognostic and immunologic features in human cancers. | 3 |
| 35348268 | 2023 | NCAPD2 promotes breast cancer progression through E2F1 transcriptional regulation of CDK1. | 8 |
| 36701707 | 2023 | NCAPD2 is a novel marker for the poor prognosis of lung adenocarcinoma and is associated with immune infiltration and tumor mutational burden. | 3 |
| 37498296 | 2023 | Non-SMC condensin I complex subunit D2 (NCAPD2) reveals its prognostic and immunologic features in human cancers. | 3 |
| 34229059 | 2021 | NCAPD2 inhibits autophagy by regulating Ca(2+)/CAMKK2/AMPK/mTORC1 pathway and PARP-1/SIRT1 axis to promote colorectal cancer. | 19 |
| 34229059 | 2021 | NCAPD2 inhibits autophagy by regulating Ca(2+)/CAMKK2/AMPK/mTORC1 pathway and PARP-1/SIRT1 axis to promote colorectal cancer. | 19 |
| 31610177 | 2020 | Non-SMC Condensin I Complex Subunit D2 Is a Prognostic Factor in Triple-Negative Breast Cancer for the Ability to Promote Cell Cycle and Enhance Invasion. | 15 |
| 31610177 | 2020 | Non-SMC Condensin I Complex Subunit D2 Is a Prognostic Factor in Triple-Negative Breast Cancer for the Ability to Promote Cell Cycle and Enhance Invasion. | 15 |
| 31056748 | 2019 | A novel homozygous splice-site variant of NCAPD2 gene identified in two siblings with primary microcephaly: The second case report. | 3 |
| 31885422 | 2019 | Non-SMC condensin I complex subunit D2 and non-SMC condensin II complex subunit D3 induces inflammation via the IKK/NF-κB pathway in ulcerative colitis. | 11 |
| 31056748 | 2019 | A novel homozygous splice-site variant of NCAPD2 gene identified in two siblings with primary microcephaly: The second case report. | 3 |
| 31885422 | 2019 | Non-SMC condensin I complex subunit D2 and non-SMC condensin II complex subunit D3 induces inflammation via the IKK/NF-κB pathway in ulcerative colitis. | 11 |
| 26878753 | 2016 | Aurora-A mediated histone H3 phosphorylation of threonine 118 controls condensin I and cohesin occupancy in mitosis. | 16 |
Citation
Dessen P
NCAPD2 (non-SMC condensin I complex subunit D2)
Atlas Genet Cytogenet Oncol Haematol. 2014-08-01
Online version: http://atlasgeneticsoncology.org/gene/54491/ncapd2-(non-smc-condensin-i-complex-subunit-d2)
