Identity
HGNC
LOCATION
14q13.1
LOCUSID
ALIAS
MOP6,PASD6,bHLHe12
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 64067
MIM: 609430
HGNC: 19311
Ensembl: ENSG00000151322
Variants:
dbSNP: 64067
ClinVar: 64067
TCGA: ENSG00000151322
COSMIC: NPAS3
RNA/Proteins
Expression (GTEx)
Protein levels (Protein atlas)
PharmGKB
| Entity ID | Name | Type | Evidence | Association | PK | PD | PMIDs |
|---|---|---|---|---|---|---|---|
| PA447199 | Bipolar Disorder | Disease | Literature, MultilinkAnnotation | associated | 24718920 |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37480305 | 2023 | SYMPTOM SEVERITY IN SCHIZOPHRENIA PATIENTS WITH NPAS3, DYSBINDIN-1 AND/OR TRIOBP PROTEIN PATHOLOGY IN THEIR BLOOD SERUM: A PANSS-BASED FOLLOW UP STUDY. | 0 |
| 37480305 | 2023 | SYMPTOM SEVERITY IN SCHIZOPHRENIA PATIENTS WITH NPAS3, DYSBINDIN-1 AND/OR TRIOBP PROTEIN PATHOLOGY IN THEIR BLOOD SERUM: A PANSS-BASED FOLLOW UP STUDY. | 0 |
| 36044858 | 2022 | Npas3 deficiency impairs cortical astrogenesis and induces autistic-like behaviors. | 3 |
| 36044858 | 2022 | Npas3 deficiency impairs cortical astrogenesis and induces autistic-like behaviors. | 3 |
| 33758288 | 2021 | Molecular characterisation of rare loss-of-function NPAS3 and NPAS4 variants identified in individuals with neurodevelopmental disorders. | 3 |
| 33758288 | 2021 | Molecular characterisation of rare loss-of-function NPAS3 and NPAS4 variants identified in individuals with neurodevelopmental disorders. | 3 |
| 30509165 | 2018 | Molecular analysis of NPAS3 functional domains and variants. | 8 |
| 30509165 | 2018 | Molecular analysis of NPAS3 functional domains and variants. | 8 |
| 28499489 | 2017 | Neuronal PAS Domain Proteins 1 and 3 Are Master Regulators of Neuropsychiatric Risk Genes. | 17 |
| 28499489 | 2017 | Neuronal PAS Domain Proteins 1 and 3 Are Master Regulators of Neuropsychiatric Risk Genes. | 17 |
| 27782878 | 2016 | NPAS1-ARNT and NPAS3-ARNT crystal structures implicate the bHLH-PAS family as multi-ligand binding transcription factors. | 39 |
| 27782878 | 2016 | NPAS1-ARNT and NPAS3-ARNT crystal structures implicate the bHLH-PAS family as multi-ligand binding transcription factors. | 39 |
| 25982957 | 2015 | Cumulative role of rare and common putative functional genetic variants at NPAS3 in schizophrenia susceptibility. | 3 |
| 25982957 | 2015 | Cumulative role of rare and common putative functional genetic variants at NPAS3 in schizophrenia susceptibility. | 3 |
| 23337948 | 2014 | A mutation in NPAS3 segregates with mental illness in a small family. | 16 |
Citation
Dessen P
NPAS3 (neuronal PAS domain protein 3)
Atlas Genet Cytogenet Oncol Haematol. 2014-08-01
Online version: http://atlasgeneticsoncology.org/gene/54508/npas3-(neuronal-pas-domain-protein-3)
