OXR1 (oxidation resistance 1)

2014-08-01  

Identity

HGNC
LOCATION
8q23.1
LOCUSID
ALIAS
CHEGDD,Nbla00307,TLDC3
FUSION GENES

Other Information

Locus ID:

NCBI: 55074
MIM: 605609
HGNC: 15822
Ensembl: ENSG00000164830

Variants:

dbSNP: 55074
ClinVar: 55074
TCGA: ENSG00000164830
COSMIC: OXR1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000164830ENST00000297447Q8N573
ENSG00000164830ENST00000312046Q8N573
ENSG00000164830ENST00000435082C9JY63
ENSG00000164830ENST00000438229E5RFD1
ENSG00000164830ENST00000442977Q8N573
ENSG00000164830ENST00000449762Q8N573
ENSG00000164830ENST00000497705Q8N573
ENSG00000164830ENST00000517566Q8N573
ENSG00000164830ENST00000517686E5RII8
ENSG00000164830ENST00000519415H0YC07
ENSG00000164830ENST00000521592E9PLW2
ENSG00000164830ENST00000531443Q8N573

Expression (GTEx)

0
5
10
15
20
25
30
35
40
45
50

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
382126062024OXR1 maintains the retromer to delay brain aging under dietary restriction.1
382126062024OXR1 maintains the retromer to delay brain aging under dietary restriction.1
361302152023A novel recessive mutation in OXR1 is identified in patient with hearing loss recapitulated by the knockdown zebrafish.3
377731362023A loss-of-function mutation in human Oxidation Resistance 1 disrupts the spatial-temporal regulation of histone arginine methylation in neurodevelopment.3
361302152023A novel recessive mutation in OXR1 is identified in patient with hearing loss recapitulated by the knockdown zebrafish.3
377731362023A loss-of-function mutation in human Oxidation Resistance 1 disrupts the spatial-temporal regulation of histone arginine methylation in neurodevelopment.3
315028102021MiR-616 promotes the progression of pancreatic carcinoma by targeting OXR1.5
315028102021MiR-616 promotes the progression of pancreatic carcinoma by targeting OXR1.5
318459862020Oxidation resistance 1 prevents genome instability through maintenance of G2/M arrest in gamma-ray-irradiated cells.7
318459862020Oxidation resistance 1 prevents genome instability through maintenance of G2/M arrest in gamma-ray-irradiated cells.7
308529772019MicroRNA-373 promotes the development of esophageal squamous cell carcinoma by targeting LATS2 and OXR1.14
316424822019Neuronal over-expression of Oxr1 is protective against ALS-associated mutant TDP-43 mislocalisation in motor neurons and neuromuscular defects in vivo.10
317857872019Loss of Oxidation Resistance 1, OXR1, Is Associated with an Autosomal-Recessive Neurological Disease with Cerebellar Atrophy and Lysosomal Dysfunction.27
308529772019MicroRNA-373 promotes the development of esophageal squamous cell carcinoma by targeting LATS2 and OXR1.14
316424822019Neuronal over-expression of Oxr1 is protective against ALS-associated mutant TDP-43 mislocalisation in motor neurons and neuromuscular defects in vivo.10

Citation

Dessen P

OXR1 (oxidation resistance 1)

Atlas Genet Cytogenet Oncol Haematol. 2014-08-01

Online version: http://atlasgeneticsoncology.org/gene/54522/oxr1-(oxidation-resistance-1)