Identity
HGNC
LOCATION
2q33.3
LOCUSID
ALIAS
ALS2CR19,PAR3B,PAR3L,PAR3beta
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 117583
HGNC: 14446
Ensembl: ENSG00000116117
Variants:
dbSNP: 117583
ClinVar: 117583
TCGA: ENSG00000116117
COSMIC: PARD3B
RNA/Proteins
Expression (GTEx)
Protein levels (Protein atlas)
PharmGKB
| Entity ID | Name | Type | Evidence | Association | PK | PD | PMIDs |
|---|---|---|---|---|---|---|---|
| PA128406956 | fluorouracil | Chemical | ClinicalAnnotation | associated | PD | 22310351 | |
| PA131285527 | oxaliplatin | Chemical | ClinicalAnnotation | associated | PD | 22310351 | |
| PA443937 | Drug Toxicity | Disease | ClinicalAnnotation | associated | PD | 22310351 | |
| PA446108 | Colorectal Neoplasms | Disease | ClinicalAnnotation | associated | PD | 22310351 |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37391589 | 2023 | VIRMA facilitates intrahepatic cholangiocarcinoma progression through epigenetic augmentation of TMED2 and PARD3B mRNA stabilization. | 1 |
| 37391589 | 2023 | VIRMA facilitates intrahepatic cholangiocarcinoma progression through epigenetic augmentation of TMED2 and PARD3B mRNA stabilization. | 1 |
| 33565714 | 2022 | Par-3 family proteins in cell polarity & adhesion. | 11 |
| 33565714 | 2022 | Par-3 family proteins in cell polarity & adhesion. | 11 |
| 27908725 | 2017 | Par3L enhances colorectal cancer cell survival by inhibiting Lkb1/AMPK signaling pathway. | 0 |
| 28443499 | 2017 | High expression of partitioning defective 3-like protein is associated with malignancy in colorectal cancer. | 1 |
| 27908725 | 2017 | Par3L enhances colorectal cancer cell survival by inhibiting Lkb1/AMPK signaling pathway. | 0 |
| 28443499 | 2017 | High expression of partitioning defective 3-like protein is associated with malignancy in colorectal cancer. | 1 |
| 21502085 | 2011 | Genome-wide association study implicates PARD3B-based AIDS restriction. | 36 |
| 21502085 | 2011 | Genome-wide association study implicates PARD3B-based AIDS restriction. | 36 |
| 20379614 | 2010 | Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. | 78 |
| 20670164 | 2010 | Association of genetic polymorphisms with hepatotoxicity in patients with childhood acute lymphoblastic leukemia or lymphoma. | 6 |
| 20677014 | 2010 | An approach based on a genome-wide association study reveals candidate loci for narcolepsy. | 19 |
| 20379614 | 2010 | Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. | 78 |
| 20670164 | 2010 | Association of genetic polymorphisms with hepatotoxicity in patients with childhood acute lymphoblastic leukemia or lymphoma. | 6 |
Citation
Dessen P
PARD3B (par-3 family cell polarity regulator beta)
Atlas Genet Cytogenet Oncol Haematol. 2014-08-01
Online version: http://atlasgeneticsoncology.org/gene/54528/pard3b-(par-3-family-cell-polarity-regulator-beta)
