Identity
HGNC
LOCATION
16q22.1
LOCUSID
ALIAS
ACS,GXVPLA2,LLPL,LPLA2,LYPLA3
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 23659
MIM: 609362
HGNC: 17163
Ensembl: ENSG00000103066
Variants:
dbSNP: 23659
ClinVar: 23659
TCGA: ENSG00000103066
COSMIC: PLA2G15
RNA/Proteins
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Glycerophospholipid metabolism | KEGG | ko00564 |
| Glycerophospholipid metabolism | KEGG | hsa00564 |
| Lysosome | KEGG | ko04142 |
| Lysosome | KEGG | hsa04142 |
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 33307060 | 2021 | Phospholipase A2 group XV activity during cardiopulmonary bypass surgery. | 1 |
| 33307060 | 2021 | Phospholipase A2 group XV activity during cardiopulmonary bypass surgery. | 1 |
| 30830753 | 2019 | Structural Basis of Lysosomal Phospholipase A(2) Inhibition by Zn(2). | 2 |
| 30830753 | 2019 | Structural Basis of Lysosomal Phospholipase A(2) Inhibition by Zn(2). | 2 |
| 29330284 | 2018 | Novel Intergenically Spliced Chimera, NFATC3-PLA2G15, Is Associated with Aggressive T-ALL Biology and Outcome. | 2 |
| 29330284 | 2018 | Novel Intergenically Spliced Chimera, NFATC3-PLA2G15, Is Associated with Aggressive T-ALL Biology and Outcome. | 2 |
| 27662254 | 2016 | Lysosomal Lipases PLRP2 and LPLA2 Process Mycobacterial Multi-acylated Lipids and Generate T Cell Stimulatory Antigens. | 18 |
| 27662254 | 2016 | Lysosomal Lipases PLRP2 and LPLA2 Process Mycobacterial Multi-acylated Lipids and Generate T Cell Stimulatory Antigens. | 18 |
| 20628086 | 2010 | Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study. | 15 |
| 20877624 | 2010 | Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression. | 20 |
| 20628086 | 2010 | Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study. | 15 |
| 20877624 | 2010 | Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression. | 20 |
| 18983494 | 2009 | Genetic variants and haplotypes of lipoprotein associated phospholipase A2 and their influence on cardiovascular disease (The Ludwigshafen Risk and Cardiovascular Health Study). | 13 |
| 19461040 | 2009 | Lipoprotein-associated phospholipase A2 and C-reactive protein for risk-stratification of patients with TIA. | 24 |
| 19913121 | 2009 | Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip. | 105 |
Citation
Dessen P
PLA2G15 (phospholipase A2 group XV)
Atlas Genet Cytogenet Oncol Haematol. 2014-08-01
Online version: http://atlasgeneticsoncology.org/gene/54539/pla2g15-(phospholipase-a2-group-xv)
