Identity
HGNC
LOCATION
19q13.11
LOCUSID
ALIAS
P76RBE,RHOBP
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 85415
MIM: 617932
HGNC: 19974
Ensembl: ENSG00000131941
Variants:
dbSNP: 85415
ClinVar: 85415
TCGA: ENSG00000131941
COSMIC: RHPN2
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000131941 | ENST00000254260 | Q8IUC4 |
| ENSG00000131941 | ENST00000588388 | K7EL35 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 33877886 | 2023 | Long Noncoding RNA RP11-89K21.1 Interacts with miR-146a/b-5p to Promote Proliferation and Gefitinib Resistance Through Regulating RHPN2 and RhoA/ROCK Pathway in Lung Adenocarcinoma. | 1 |
| 33877886 | 2023 | Long Noncoding RNA RP11-89K21.1 Interacts with miR-146a/b-5p to Promote Proliferation and Gefitinib Resistance Through Regulating RHPN2 and RhoA/ROCK Pathway in Lung Adenocarcinoma. | 1 |
| 36210710 | 2022 | [RHPN2 is highly expressed in osteosarcoma cells to promote cell proliferation and migration and inhibit apoptosis]. | 0 |
| 36210710 | 2022 | [RHPN2 is highly expressed in osteosarcoma cells to promote cell proliferation and migration and inhibit apoptosis]. | 0 |
| 34382920 | 2021 | P76RBE silencing inhibits ovarian cancer cell proliferation, migration, and invasion via suppressing the integrin β1/NF-κB pathway. | 1 |
| 34382920 | 2021 | P76RBE silencing inhibits ovarian cancer cell proliferation, migration, and invasion via suppressing the integrin β1/NF-κB pathway. | 1 |
| 31847864 | 2019 | Human bone marrow mesenchymal stem cells-derived microRNA-205-containing exosomes impede the progression of prostate cancer through suppression of RHPN2. | 42 |
| 31847864 | 2019 | Human bone marrow mesenchymal stem cells-derived microRNA-205-containing exosomes impede the progression of prostate cancer through suppression of RHPN2. | 42 |
| 29949196 | 2018 | Genetic variants of MGMT, RHPN2, and FAM49A contributed to susceptibility of nonsyndromic orofacial clefts in a Chinese population. | 3 |
| 29949196 | 2018 | Genetic variants of MGMT, RHPN2, and FAM49A contributed to susceptibility of nonsyndromic orofacial clefts in a Chinese population. | 3 |
| 25799222 | 2015 | Association between GWAS-identified genetic variations and disease prognosis for patients with colorectal cancer. | 14 |
| 26349980 | 2015 | Analyzing large-scale samples highlights significant association between rs10411210 polymorphism and colorectal cancer. | 14 |
| 25799222 | 2015 | Association between GWAS-identified genetic variations and disease prognosis for patients with colorectal cancer. | 14 |
| 26349980 | 2015 | Analyzing large-scale samples highlights significant association between rs10411210 polymorphism and colorectal cancer. | 14 |
| 23774217 | 2013 | RHPN2 drives mesenchymal transformation in malignant glioma by triggering RhoA activation. | 35 |
Citation
Dessen P
RHPN2 (rhophilin Rho GTPase binding protein 2)
Atlas Genet Cytogenet Oncol Haematol. 2014-08-01
Online version: http://atlasgeneticsoncology.org/gene/54582/rhpn2-(rhophilin-rho-gtpase-binding-protein-2)
