Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 9853
MIM: 611053
HGNC: 23625
Ensembl: ENSG00000198853
Variants:
dbSNP: 9853
ClinVar: 9853
TCGA: ENSG00000198853
COSMIC: RUSC2
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000198853 | ENST00000361226 | Q8N2Y8 |
| ENSG00000198853 | ENST00000455600 | Q8N2Y8 |
Expression (GTEx)
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 34432492 | 2021 | RUSC2 and WDR47 oppositely regulate kinesin-1-dependent distribution of ATG9A to the cell periphery. | 9 |
| 34432492 | 2021 | RUSC2 and WDR47 oppositely regulate kinesin-1-dependent distribution of ATG9A to the cell periphery. | 9 |
| 31932478 | 2020 | EHD1 and RUSC2 Control Basal Epidermal Growth Factor Receptor Cell Surface Expression and Recycling. | 6 |
| 32744243 | 2020 | Crystal structure of the FYCO1 RUN domain suggests possible interfaces with small GTPases. | 3 |
| 31932478 | 2020 | EHD1 and RUSC2 Control Basal Epidermal Growth Factor Receptor Cell Surface Expression and Recycling. | 6 |
| 32744243 | 2020 | Crystal structure of the FYCO1 RUN domain suggests possible interfaces with small GTPases. | 3 |
| 30905672 | 2019 | Rab35/ACAP2 and Rab35/RUSC2 Complex Structures Reveal Molecular Basis for Effector Recognition by Rab35 GTPase. | 8 |
| 31199889 | 2019 | Circ_RUSC2 upregulates the expression of miR-661 target gene SYK and regulates the function of vascular smooth muscle cells. | 19 |
| 30905672 | 2019 | Rab35/ACAP2 and Rab35/RUSC2 Complex Structures Reveal Molecular Basis for Effector Recognition by Rab35 GTPase. | 8 |
| 31199889 | 2019 | Circ_RUSC2 upregulates the expression of miR-661 target gene SYK and regulates the function of vascular smooth muscle cells. | 19 |
| 30262884 | 2018 | AP-4 vesicles contribute to spatial control of autophagy via RUSC-dependent peripheral delivery of ATG9A. | 72 |
| 30262884 | 2018 | AP-4 vesicles contribute to spatial control of autophagy via RUSC-dependent peripheral delivery of ATG9A. | 72 |
| 27238570 | 2016 | EGF-stimulated activation of Rab35 regulates RUSC2-GIT2 complex formation to stabilize GIT2 during directional lung cancer cell migration. | 19 |
| 27612186 | 2016 | Loss-of-function mutation in RUSC2 causes intellectual disability and secondary microcephaly. | 7 |
| 27238570 | 2016 | EGF-stimulated activation of Rab35 regulates RUSC2-GIT2 complex formation to stabilize GIT2 during directional lung cancer cell migration. | 19 |
Citation
Dessen P
RUSC2 (RUN and SH3 domain containing 2)
Atlas Genet Cytogenet Oncol Haematol. 2014-08-01
Online version: http://atlasgeneticsoncology.org/gene/54597/rusc2-(run-and-sh3-domain-containing-2)
