Identity
HGNC
LOCATION
14q32.2
LOCUSID
ALIAS
C14orf154,hSETD3
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 84193
MIM: 615671
HGNC: 20493
Ensembl: ENSG00000183576
Variants:
dbSNP: 84193
ClinVar: 84193
TCGA: ENSG00000183576
COSMIC: SETD3
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 36503048 | 2023 | CircSETD3 mediates acquired resistance to gefitinib in non-small lung cancer cells by FXR1/ECT2 pathway. | 2 |
| 37581408 | 2023 | The Role of Trp79 in β-Actin on Histidine Methyltransferase SETD3 Catalysis. | 0 |
| 36503048 | 2023 | CircSETD3 mediates acquired resistance to gefitinib in non-small lung cancer cells by FXR1/ECT2 pathway. | 2 |
| 37581408 | 2023 | The Role of Trp79 in β-Actin on Histidine Methyltransferase SETD3 Catalysis. | 0 |
| 35018513 | 2022 | Stabilization of SETD3 by deubiquitinase USP27 enhances cell proliferation and hepatocellular carcinoma progression. | 9 |
| 35142326 | 2022 | Importance of Ile71 in β-actin on histidine methyltransferase SETD3 catalysis. | 1 |
| 35550916 | 2022 | Structure-function conservation between the methyltransferases SETD3 and SETD6. | 1 |
| 35891342 | 2022 | Proteolytic Activities of Enterovirus 2A Do Not Depend on Its Interaction with SETD3. | 1 |
| 35018513 | 2022 | Stabilization of SETD3 by deubiquitinase USP27 enhances cell proliferation and hepatocellular carcinoma progression. | 9 |
| 35142326 | 2022 | Importance of Ile71 in β-actin on histidine methyltransferase SETD3 catalysis. | 1 |
| 35550916 | 2022 | Structure-function conservation between the methyltransferases SETD3 and SETD6. | 1 |
| 35891342 | 2022 | Proteolytic Activities of Enterovirus 2A Do Not Depend on Its Interaction with SETD3. | 1 |
| 33157163 | 2021 | The methyltransferase SETD3-mediated histidine methylation: Biological functions and potential implications in cancers. | 7 |
| 33157163 | 2021 | The methyltransferase SETD3-mediated histidine methylation: Biological functions and potential implications in cancers. | 7 |
| 31911441 | 2020 | An engineered variant of SETD3 methyltransferase alters target specificity from histidine to lysine methylation. | 6 |
Citation
Dessen P
SETD3 (SET domain containing 3, actin histidine methyltransferase)
Atlas Genet Cytogenet Oncol Haematol. 2014-08-01
Online version: http://atlasgeneticsoncology.org/gene/54611/setd3-(set-domain-containing-3-actin-histidine-methyltransferase)
