Identity
HGNC
LOCATION
2p11.2
LOCUSID
ALIAS
PSP-B,SFTB3,SFTP3,SMDP1,SP-B
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 6439
MIM: 178640
HGNC: 10801
Ensembl: ENSG00000168878
Variants:
dbSNP: 6439
ClinVar: 6439
TCGA: ENSG00000168878
COSMIC: SFTPB
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 36460583 | 2023 | SFTPB (rs11130866) and NR3C1 (rs41423247) gene variants as potential clinical biomarkers for personalized treatment strategy selection in patients with severe COVID-19 pneumonia. | 4 |
| 36460583 | 2023 | SFTPB (rs11130866) and NR3C1 (rs41423247) gene variants as potential clinical biomarkers for personalized treatment strategy selection in patients with severe COVID-19 pneumonia. | 4 |
| 35121658 | 2022 | A dominant negative variant of RAB5B disrupts maturation of surfactant protein B and surfactant protein C. | 5 |
| 35300983 | 2022 | Pulmonary surfactant protein B carried by HDL predicts incident CVD in patients with type 1 diabetes. | 5 |
| 35689653 | 2022 | Silica nanoparticle exposure inhibits surfactant protein A and B in A549 cells through ROS-mediated JNK/c-Jun signaling pathway. | 1 |
| 35121658 | 2022 | A dominant negative variant of RAB5B disrupts maturation of surfactant protein B and surfactant protein C. | 5 |
| 35300983 | 2022 | Pulmonary surfactant protein B carried by HDL predicts incident CVD in patients with type 1 diabetes. | 5 |
| 35689653 | 2022 | Silica nanoparticle exposure inhibits surfactant protein A and B in A549 cells through ROS-mediated JNK/c-Jun signaling pathway. | 1 |
| 33719563 | 2021 | A primate-specific RNA-binding protein (RBMXL3) is involved in glucocorticoid regulation of human pulmonary surfactant protein B (SP-B) mRNA stability. | 0 |
| 33729612 | 2021 | Pulmonary surfactant-associated protein B regulates prostaglandin-endoperoxide synthase-2 and inflammation in chronic obstructive pulmonary disease. | 2 |
| 34286505 | 2021 | Immunohistochemical findings in the lungs of COVID-19 subjects: evidence of surfactant dysregulation. | 5 |
| 33719563 | 2021 | A primate-specific RNA-binding protein (RBMXL3) is involved in glucocorticoid regulation of human pulmonary surfactant protein B (SP-B) mRNA stability. | 0 |
| 33729612 | 2021 | Pulmonary surfactant-associated protein B regulates prostaglandin-endoperoxide synthase-2 and inflammation in chronic obstructive pulmonary disease. | 2 |
| 34286505 | 2021 | Immunohistochemical findings in the lungs of COVID-19 subjects: evidence of surfactant dysregulation. | 5 |
| 31851120 | 2020 | Regulatory Roles of Human Surfactant Protein B Variants on Genetic Susceptibility to Pseudomonas Aeruginosa Pneumonia-Induced Sepsis. | 8 |
Citation
Dessen P
SFTPB (surfactant protein B)
Atlas Genet Cytogenet Oncol Haematol. 2014-08-01
Online version: http://atlasgeneticsoncology.org/gene/54615/submit-meetings/teaching-explorer/
