Identity
HGNC
LOCATION
13q12.11
LOCUSID
ALIAS
C13orf3,RAMA1
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 221150
HGNC: 20262
Ensembl: ENSG00000165480
Variants:
dbSNP: 221150
ClinVar: 221150
TCGA: ENSG00000165480
COSMIC: SKA3
RNA/Proteins
Expression (GTEx)
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38228236 | 2024 | Spindle and kinetochore-related complex subunit 3 has a protumour function in osteosarcoma by activating the Notch pathway. | 0 |
| 38228236 | 2024 | Spindle and kinetochore-related complex subunit 3 has a protumour function in osteosarcoma by activating the Notch pathway. | 0 |
| 36728910 | 2023 | Transcription factor ZEB1 regulates PLK1-mediated SKA3 phosphorylation to promote lung cancer cell proliferation, migration and cell cycle. | 4 |
| 37821935 | 2023 | Hypoxia-induced SKA3 promoted cholangiocarcinoma progression and chemoresistance by enhancing fatty acid synthesis via the regulation of PAR-dependent HIF-1a deubiquitylation. | 3 |
| 37973787 | 2023 | Specific intracellular retention of circSKA3 promotes colorectal cancer metastasis by attenuating ubiquitination and degradation of SLUG. | 1 |
| 36728910 | 2023 | Transcription factor ZEB1 regulates PLK1-mediated SKA3 phosphorylation to promote lung cancer cell proliferation, migration and cell cycle. | 4 |
| 37821935 | 2023 | Hypoxia-induced SKA3 promoted cholangiocarcinoma progression and chemoresistance by enhancing fatty acid synthesis via the regulation of PAR-dependent HIF-1a deubiquitylation. | 3 |
| 37973787 | 2023 | Specific intracellular retention of circSKA3 promotes colorectal cancer metastasis by attenuating ubiquitination and degradation of SLUG. | 1 |
| 35546682 | 2022 | SKA3 is a prognostic biomarker and associated with immune infiltration in bladder cancer. | 2 |
| 35546682 | 2022 | SKA3 is a prognostic biomarker and associated with immune infiltration in bladder cancer. | 2 |
| 33423159 | 2021 | Spindle and kinetochore‑associated complex subunit 3 accelerates breast cancer cell proliferation and invasion through the regulation of Akt/Wnt/β-catenin signaling. | 4 |
| 33760206 | 2021 | Upregulation of SKA3 enhances cell proliferation and correlates with poor prognosis in hepatocellular carcinoma. | 6 |
| 33775353 | 2021 | Circ-SKA3 upregulates ID3 expression by decoying miR-326 to accelerate the development of medulloblastoma. | 12 |
| 33895155 | 2021 | SKA3 promotes glioblastoma proliferation and invasion by enhancing the activation of Wnt/β-catenin signaling via modulation of the Akt/GSK-3β axis. | 8 |
| 34045512 | 2021 | Transcript levels of spindle and kinetochore-associated complex 1/3 as prognostic biomarkers correlated with immune infiltrates in hepatocellular carcinoma. | 5 |
Citation
Dessen P
SKA3 (spindle and kinetochore associated complex subunit 3)
Atlas Genet Cytogenet Oncol Haematol. 2014-08-01
Online version: http://atlasgeneticsoncology.org/gene/54622/ska3-(spindle-and-kinetochore-associated-complex-subunit-3)
